摘要
目的探讨缬沙坦和氨氯地平在社区老年原发高血压合并糖尿病治疗中的应用效果。方法选取我院2014年6月~2015年6月收治的原发高血压合并糖尿病患者120例作为研究对象,利用随机数字表法将其分成3组,每组40例。A组给予缬沙坦治疗,B组给予氨氯地平治疗,C组给予缬沙坦联合氨氯地平治疗。治疗12周后比较3组临床疗效、血压水平和糖尿病指标变化情况。结果治疗后C组总有效率为95.00%,显著高于A组和B组（P〈0.01）;治疗后3组患者的SBP、DBP、FBG、2h PBG、FINS、Hb A1C均有显著降低（P〈0.05）,且C组的降低更为显著（P〈0.01）。结论缬沙坦和氨氯地平联合使用可有效治疗社区老年原发高血压合并糖尿病,值得临床推广应用。
Objective To investigate the application effect of valsartan combined with amlodipine in the treatment of community elderly patients with primary hypertension and diabetes mellitus. Methods 120 patients with primaryhy pretension complicated with diabetes treated in our hospital from June 2014 to June 2015 were selected as the research objects, and were divided into three groups by the random number table method, 40 cases in each group. Patients in group A were treated with valsartan, patients in group B were given amlodipine treatment, and patients in group C were given valsartan combined with a mlodipine. After 12 weeks of treatment, the clinical efficacy, blood pressure level and the changes of diabetic parameters were compared between the three groups. Results After treatment, the total effective rate of C group was 95%, which was significantly higher than that of A group and B group（P〈0.01）. After treatment, SBP, DBP, FBG, 2h PBG, FINS, Hb A1 C of the three groups were significantly reduced（P〈0.05）, and those of C group decreased more significantly（P〈0.01）. Conclusion The valsartan combined with amlodipine in the treatment of community elderly patients is effective, it is worthy of clinical application.
出处
《中国医药科学》
2016年第8期68-70,共3页
China Medicine And Pharmacy
