摘要
目的:探讨影响纳米炭在乳腺癌前哨淋巴结中活检成功率的因素。方法:选取河南科技大学第一附属医院2013年1月至2015年3月收治的乳腺癌患者270例,应用纳米炭对其行前哨淋巴结活检术(sentinel lymph node biopsy,SLNB),并对其影响因素进行logistic分析。结果:SLN活检成功率为92.2%,准确度为97.6%,敏感度为93.1%,假阴性率为6.8%。年龄、原发肿瘤病灶、体质量指数、腋窝淋巴结状况、SLN数量及病理分级等是影响活检成功的相关因素(均P<0.05),其中体质量指数、年龄和SLN数量是影响活检成功率的3个独立因素(均P<0.05),而活检史、肿瘤部位、受累侧、注射部位及化学治疗史对活检成功率影响不大(均P>0.05)。结论:纳米炭示踪法是乳腺癌SLNB的可靠方法,患者的体质量指数、年龄和淋巴结转移数对活检成功率的影响较大。
Objective： To explore the factors affecting the successful rate of nano-carbon in sentinel lymph node biopsy.Methods： A total of 270 patients with breast cancer, who were treated in First Aff i litated Hospital of Henan University of Science and Technology from January 2013 to March 2015, were chosen and given sentinel lymph node biopsy（SLN） with nano-carbon, and the infl uencial factors were examined by logistic analysis.Results： Successful rate of biopsy, accuracy, sensitivity and false negative rate was 92.2%, 97.6%,93.1% and 6.8%, respectively. Age, primary tumor lesions, body mass index, axillary lymph node status, number of SLN and pathological grade were the factors affetcing successful biopsy（all P0.05）, and body mass index, age, and number of SLN were three independent factors affecting the successful rate of biopsy（all P0.05）. The history of biopsy, tumor location, affected sides, injection sites and chemotherapy showed little effect on the successful rate of biopsy（all P 0.05）.Conclusion： Nano-carbon tracer method is a reliable method in sentinel lymph node biopsy. The body mass index, age, and number of lymph node metastasis greatly impact the successful rate of biopsy.
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2016年第4期411-416,共6页
Journal of Central South University ：Medical Science
