摘要
目的分析妇产科住院患者医院感染病原菌分布特点及耐药性,以期为妇产科患者临床感染性疾病的治疗提供合理用药依据,为妇产科医院感染的预防控制工作提供参考。方法选取2003年1月-2015年3月妇产科住院患者1 028例,统计患者医院感染率,对医院感染的病原菌分布及药物敏感性进行分析。结果 1 028例住院患者共发生感染58例、64例次,感染率为5.64%、例次感染率为6.23%,感染部位以呼吸道、泌尿道和宫腔感染为主,分别占34.4%、29.7%、26.6%,共分离出病原菌53株,其中革兰阴性菌36株占67.92%,革兰阳性菌10株占18.87%,真菌7株占13.21%;肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌为主要病原菌,分别占20.75%、18.87%、15.09%;肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌对美罗培南、亚胺培南的耐药率为0,对头孢唑林、头孢他啶、头孢噻肟、庆大霉素的耐药率>60.00%,铜绿假单胞菌对头孢吡肟耐药率为0。结论妇产科医院临床病原菌分布较为广泛,患者感染率较高,病原菌的耐药性较强,应重视临床感染预防控制工作。
OBJECTIVE To investigate the distribution and drug resistance of pathogens causing nosocomial infections in patients of department of obstetrics and gynecology so as to provide guidance for reasonable use of antibiotics for treatment of clinical infectious diseases and prevent the nosocomial infections in the department of obstetrics and gynecology.METHODS A total of 1 028 patients who were hospitalized the department of obstetrics and gynecology from Jan 2003 to Mar 2015 were enrolled in the study,then the incidence rates of nosocomial infections were statistically analyzed,and the distribution and drug susceptibility of the pathogens causing the nosocomial infections were observed.RESULTS Of the 1 028 hospitalized patients,58（64case-times）had nosocomial infections with the infection rate of 5.64% and the case-time infection rate of 6.23%,of whom 34.4% had respiratory tract infections,29.7% had urinary tract infections,and 26.6% had intrauterine infections.Totally 53 strains of pathogens were isolated,including 36（67.92%）strains of gram-negative bacteria,10（18.87%）strains of gram-positive bacteria,and 7（13.21%）strains of fungi;the Klebsiella pneumoniae,Escherichia coli,and Pseudomonas aeruginosa were the major species of pathogens,accounting for 20.75%,18.87%,and 15.09%,respectively.The results of drug susceptibility testings indicated that the drug resistance rates of the K.pneumoniae,E.coli,and P.aeruginosato meropenem and imipenem were 0,the drug resistance rates to cefazolin,ceftazidime,cefotaxime,and gentamicin were more than 60.00%,and the drug resistance rate of the P.aeruginosato cefepime was0.CONCLUSIONThe spectrum of the clinical pathogens isolated from the department of obstetrics and gynecology is broad,the infection rate is high in the patients,and the pathogens are highly drug-resistant.It is necessary to pay attention to the prevention and control of clinical infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第9期2126-2127,2133,共3页
Chinese Journal of Nosocomiology
基金
河南省卫生厅基金资助项目(WJ01564)
关键词
妇产科
患者
医院感染
病原菌
分布
Obstetrics and gynecology department
Patient
Nosocomial infection
Pathogen
Distribution
