摘要
目的探讨脑梗死患者溶栓治疗后发生脑微出血的危险因素。方法选取2010年10月~2015年10月进行溶栓治疗的脑梗死患者124例,按治疗后是否发生脑微出血分为两组,微出血组26例,对照组98例,分别采用χ2检验及Logistic回归分析法分析治疗后脑微出血的危险因素。结果单因素分析显示,年龄≥60岁、合并高血压、合并糖尿病、房颤、大面积梗死是治疗后脑微出血的影响因素（P〈0.001）;多因素Logistic回归分析显示,合并高血压、合并糖尿病、房颤、大面积梗死均对治疗后脑微出血有影响（P〈0.05或0.01）。结论脑梗死患者溶栓治疗后发生脑微出血与多种因素有关,应引起临床重视,治疗前采取积极预防措施,提高溶栓治疗的安全性。
Objective To investigate the risk factors of cerebral microbleeds after thrombolytic therapy in patients with cerebral infarction.Methods 124 cases of cerebral infarction treated with thrombolytic therapy from October,2010 to Octo- ber,2015 were selected.And they were divided into microbleeds group （26 cases） and control group （98 cases） according to the appearance of cerebral microbleeds after treatment.Then, the risk factors of cerebral microbleeds after treatment were ana- lyzed by ~2 test and Logistic regression analysis, respectively.Results Univariate analysis showed that age i---60 years, com- bined with hypertension, combined with diabetes, atrial fibrillation, a large area of cerebral infarction were influencing factors of cerebral microbleeds after treatment（ P〈0.001 ）.Multivariate Logistic regression analysis showed that combined with hyper- tension, combined with diabetes, atrial fibrillation and a large area of cerebral infarction could affect cerebral microbleeds after treatment（P〈0. 05 or 0.01 ） .Conclusion Cerebral microbleeds after thrombolysis in patients with cerebral infarction is relat- ed to many factors.Thus, clinical attention should be paid to take active preventive measures to improve the safety of thrombo- lytic therapy before treatment.
出处
《右江医学》
2016年第2期164-167,共4页
Chinese Youjiang Medical Journal
关键词
脑梗死
溶栓
脑微出血
影响因素
cerebral infarction
thrombolysis
cerebral microbleeds
influence factors
