摘要
目的：对儿童急性荨麻疹的临床分析及糖皮质激素的应用分析进行探讨,为临床治疗和诊断提供参考。方法：选择我院收治的儿童急性荨麻疹患者100例作为本次研究的对象,这100例患者的收治时间在2013年2月1日~2014年2月1日,对这100例患者的临床资料进行回顾性和系统性分析,探讨其临床特点,随机将这100例患者分成实验组和对照组,每组50例,对照组给予常规抗生素治疗,实验组给予糖皮质激素治疗,并在治疗结束后,对比分析两组的治疗总有效率、皮疹消失时间及腹痛消失时间。结果：①100例儿童急性荨麻疹患者中,上呼吸道感染41例,占41.00%;肺炎16例,占16.00%;扁桃体炎34例,占34.00%;急性胃肠炎6例,占6.00%;化脓性中耳炎3例,占3.00%。②100例儿童急性荨麻疹患者均表现出全身泛发性鲜红色风团或水肿性红斑症状,以发热、咽喉疼痛、浅表淋巴结肿大、咳嗽、腹痛、呕吐、胸闷等为主要临床表现,分别占46.00%、56.00%、32.00%、45.00%、47.00%、27.00%及23.00%。③100例儿童急性荨麻疹患者的血常规白细胞均伴有不同程度的升高,白细胞上升54例,占54.00%;中性粒细胞上升36例,占36.00%;淋巴细胞上升6例,占6.00%;淋巴细胞和白细胞均上升4例,占4.00%。④实验组治疗总有效率为96.00%（48/50）,对照组治疗总有效率为78.00%（39/50）,P〈0.05,差异具有统计学意义;实验组皮疹消失时间及腹痛消失时间均低于对照组（P〈0.05）,差异具有统计学意义。结论：儿童急性荨麻疹以呼吸道感染为主,患者常伴发热、咽喉疼痛、浅表淋巴结肿大、咳嗽、腹痛、呕吐、胸闷等临床表现,实验室检查可见血常规白细胞伴有不同程度上升,给予糖皮质激素治疗具有积极的疗效,可有效提高治疗效果,缩短皮疹消失时间和腹痛消失时间,促进恢复健康。
Objective ：To investigate the clinical analysis of acute urticaria in children and analyze the application of glucoeorticoid, to provide reference for clinical treatment and diagnosis of acute urticaria in children. Methods： 100 cases of children with acute urticaria patients admitted to our hospital as the research object, the 100 cases of patients were in February 2013 1, 2014 to February 1 during the day, the clinical data of 100 eases of patients for review and systematic analysis, to explore the clinical characteristics, random 100 cases patients were divided into experimental group and control group, each group accounted for 50 cases, control group was given routine antibiotic treatment, the experimental group given g]ucocorticoid treatment, and at the end of the treatment, comparative analysis of two groups of the total efficiency of the treatment, the rash disappeared time and pain disappearing time. ResultS：of 100 cases of acute childhood acute urticaria patients, upper respiratory tract infection in patients with a total of 41 cases, accounting for total ratio of 41.00%; pneumonia in patients with a total of 16 cases, accounting for the total ratio of 16.00%; tonsillitis patients with a total of 34 cases, accounting for total than 34.00% ; 6 cases of patients with acute gastroenteritis, accounting for the total ratio of 6.00% ; suppurative otitis media in patients with a total of 3 cases, accounting for the total ratio of 3.00%. 2 100 cases of patients with acute urticaria showed generalized of bright red wheal or edema lupus symptoms, fever, sore throat, shallow table lymph node enlargement, cough, abdominal pain, vomiting, chest tightness, etc. as the main clinical manifestations, respectively, of the total ratio of 46.00%, 56.00%, 32.00%, 45.00%, 47.00, 27.00% and 23.00%. 3 100 cases of children with acute urticaria patients white blood cells are associated with varying degrees of increase, ]eukocytes increased in a total of 54 cases, accounting for total ratio of 54.00% ; increased neutrophils in 36 cases, accounting for the total ratio of 36.00% ; lymphocytes increased and a total of six cases, accounting for total than 6.00% ; lymph cells and white blood cells were increased and a total of 4 cases, accounting for the total ratio of 4.00%. The treatment of 4 patients in the experimental group, the total effective rate was 96% （48 / 50）, the control group of patients with treatment total efficiency is 78% （39）, P 〈 0.05, with statistical significance; patients in the experimental group the rash disappeared time and pain disappearing time were lower than the control group （P 〈 0.05）, the difference has statistical significance. Conclusion： children with acute urticaria with respiratory infection was the main infection, patients often accompanied by fever, sore throat, shallow table lymph node enlargement, cough, abdominal pain, vomiting, chest tightness, etc. clinical manifestations and laboratory examination showed white blood cells associated with different degrees of rise, giving children with acute urticaria patients with glucocorticoid therapy has a positive effect, can effectively improve the treatment effect of patients, shorten the patients the rash disappeared and pain disappearing time, promote the patient further recovery.
出处
《北方药学》
2016年第5期8-9,共2页
Journal of North Pharmacy
基金
宝安区科技计划项目
项目编号2013289
