摘要
纳米混悬技术为改善难溶性中药有效成分和有效部位的溶解度和生物利用度提供了新的方法,在中药领域的应用与发展中,是实现中药现代化、国际化的有效途径之一。主要对中药纳米混悬给药系统的制备方法、固化研究和应用进行综述,并分析了目前所存在的问题,提出了解决问题的设想,以期促进纳米混悬技术在中药制剂中的开发与完善,扩大中药的应用范围。
Nanosuspension technology has provided a new method for improving the solubility and bioavailability of the effective components and the effective parts in Chinese materia medica （CMM）. It is one of the effective ways to realize the modernization and internationalization in the application and development of CMM. This article mainly summarizes the preparation method, curing research, application of CMM nanosuspension drug delivery system, analyzes the existing problems, and puts forward some ideas, in order to promote the development and perfection of nanosuspension technology in CMM, and expand the scope of application of CMM.
出处
《中草药》
CAS
CSCD
北大核心
2016年第6期865-871,共7页
Chinese Traditional and Herbal Drugs
基金
四川省教育厅重点项目(15ZA0094)
成都中医药大学科研实践创新课题重点项目(ky2015-004)
关键词
纳米混悬技术
中药制剂
生物利用度
溶解度
固化
nanosuspension technology
Chinese materia medica preparation
bioavailability
solubility
solidification
