摘要
目的了解结核病信息管理系统报告的20052014年四川省结核病患者治疗队列死亡流行现状及变化趋势。方法以2005年i月1日至2014年12月31日中国结核病信息管理系统中所有四川省登记的649328例结核病患者作为研究对象,对结核病总死亡、因结核病死亡和因非结核病死亡情况及三间分布、不同诊断和治疗特征患者因结核病死亡情况进行分析。不同年份间结核病患者病死率进行X2趋势检验,对不同诊断、治疗特征结核病患者病死率进行X2检验。P为双侧概率,检验水准a=0.05。结果四川省结核病患者总病死率从2005年的1.02%(630/61856)下降至2014年的0.93%(497/53260),差异有统计学意义(X2趋势=4.66,P=0.031)。其中,结核病病死率从0.42%(262/61856)下降至0.20%(109/53260),差异有统计学意义(X2趋势=39.02,P=0.000);非结核病病死率从0.59%(368/61856)上升至0.73%(388/53260),差异有统计学意义(X2趋势=47.59,P=0.000)。结核病总病死率男性(1.05%,4828/458249)高于女性(0.73%,1390/191058),差异有统计学意义(X2=151.12,p=0.000);结核病病死率和非结核病病死率均随年龄增加而上升,差异均有统计学意义(瞧l蚺分别为579.10和1538.33,P值均为0.000)。川中(1.21%,2406/198901)和川西地区(1.14%,887/78124)结核病患者总病死率高于川南(0.99%,1525/154052)和川东北(o.64%,1400/218251),差异有统计学意义(X2=391.10,P=0.000);复治患者因结核病病死率(0.48%,307/64276)高于初治患者(0.29%,1681/585052),差异有统计学意义(X2=68.72,P=0.000);重症患者因结核病病死率(0.57%,383/67683)高于非重症患者(o.28%,1605/581645),差异有统计学意义(X2=254.03,P=O.000)。结论四川省结核病患者总病死率呈逐年下降的趋势,但在川中、川西地区和老年人群中总病死率较高,血行播散性肺结核、涂阳、复治和重症患者结核病病死率较高。
Objective To analyze epidemiology features and trend of deaths among registered tuberculosis (TB) patients in Sichuan province from 2005 to 2014. Methods Data of all 649 328 TB cases registered in Sichuan province were obtained from Chinese Tuberculosis Information System bewteen January 1, 2005 and December 31, 2014. Total fatality rate, rates of death from TB and other reasons were analyzed, the rate of death from TB in pa tients with different diagnosis and treatment were also analyzed. Results During 2005 2014, all the compared data were statistically significant the total fatality rate declined from 1.02% (630/61 856) to 0. 93% (497/53 260) (X^2trend =4. 66, P=0. 031), the rate of death from TB declined from 0.42% (262/61 856) to 0.20%0 (109/53 260) (X^2trend=39.02,P 0. 000), the rate of death from other reasons increased from 0.59% (368/61 856) to 0.73% (388/53 260) (X^2trend=47. 59, P=0. 000) ; the total fatality rate of males (1.05%, 4828/458 249) was higher than that of females (0. 73%, 1390/191 058) (X^2 = 151.12, P=0. 000) ; the rate of death from TB and other reasons both increased with age (X2 were 579.10 and 1538.33, respectively, both P values 0. 000) ; the total fatality rates in central Sichuan (1.21%, 2406/198 901) and in west Sichuan (1.14%, 887/78 124) were higher than those in south Sichuan (0.99%, 1525/154 052) and the northeast Sichuan (0.64%, 1400/218 251) (X^2=391.10, P=0. 000); of the patients undergoing treatment, the rate of death from TB in recurrent cases (0.48%, 307/64 276) were higher than that in first attack cases (0.29%, 1681/585 052) (X2=68.72, P=0. 000) ; and the rate of death from TB in severe cases (0.57%, 383/67 683) was higher than that in non-severe cases (0.28%, 1605/581 645) (X^2=254.03,P=0. 000) Conclusion In recent years, the total fatality rate of TB patients in Sichuan is decending; however, it is still high in central and south Sichuan, and still high in the older populations. Furthermore, the rate of death from TB is relatively higher in hematogenous pulmonary TB patients, smear positive TB patients, recurrent cases and se vere cases.
出处
《中国防痨杂志》
CAS
2016年第5期398-404,共7页
Chinese Journal of Antituberculosis
关键词
结核
肺/病死率
流行病学研究
四川省
Tuberculosis, pulmonary/fatality rate
Epidemiologic studies
Sichuan province