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2015年版《慢性乙型肝炎防治指南》——慢性乙型肝炎抗病毒治疗指南解读 被引量:73

Interpretation of 2015 Guideline of Prevention and Treatment for Chronic Hepatitis B
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摘要 本文对2015年版《慢性乙型肝炎防治指南》中慢性乙型肝炎抗病毒治疗部分进行了解读。新版指南更加注重循证医学证据,强调预防和母婴阻断的重要性。在治疗目标上强调了对于部分适合的患者应尽可能追求慢性乙型肝炎的临床治愈。对持续乙型肝炎病毒(HBV)DNA阳性,达不到治疗标准的患者,建议将观察年龄调整为>30岁。治疗上更加强调适宜患者应积极抗病毒治疗,并将强效低耐药作为一线药物的推荐。 The paper interpreted antiviral treatment of 2015 Guideline of Prevention and Treatment for Chronic Hepatitis B. The new guideline emphasizes more on evidence- based medicine and the importance of prevention and the interdiction of maternal- neonatal transmission. In terms of treatment objectives,it emphasizes that the clinical cure of chronic hepatitis B should be pursued for eligible patients if possible. For patients with continuous DNA positiveness in hepatitis B virus who can not meet treatment standards,it is recommended to adjust their observation age to 〉 30 years old. It highlights positive antiviral treatment for eligible patients and recommends high- potency and low- resistance drugs as first- line drugs.
作者 孟庆华 侯维
出处 《中国全科医学》 CAS CSCD 北大核心 2016年第14期1613-1615,共3页 Chinese General Practice
关键词 乙型肝炎 慢性 乙型肝炎病毒 抗病毒药 指南 Hepatitis B chronic Hepatitis B virus Antiviral agents Guidebooks
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  • 1王贵强,王福生,成军,任红,庄辉,孙剑,李兰娟,李杰,孟庆华,赵景民,段钟平,侯金林,贾继东,唐红,盛吉芳,彭劼,鲁凤民,谢青,魏来.慢性乙型肝炎防治指南(2015年版)[J].中华实验和临床感染病杂志(电子版),2015,9(5):1-19. 被引量:521
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  • 3Zhang H, Pan CQ, Pang Q, et al. Telbivudine or lamivudine use in late pregnancy safely reduces perinatal transmission of hepatitis B virus in real-lifepractice [J]. Hepatology, 2014, 60 (2): 468-476.
  • 4Greenup A J, Tan PK, Nguyen V, et al. Efficacy and safety of tenofovir disoproxil fumarate in pregnancy to prevent perinatal transmission of hepatitis B virus [J]. J Hepatol, 2014, 61 (3): 502 - 507.

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