摘要
目的:探讨联合应用40℃3%氯化钠溶液鼻腔冲洗与丙酸氟替卡松鼻喷雾剂治疗过敏性鼻炎(AR)的疗效。方法:对160例确诊为常年性AR患者的临床资料进行回顾性分析,其中单纯应用丙酸氟替卡松鼻喷雾剂80例为对照组,40℃3%氯化钠溶液鼻腔冲洗联合应用丙酸氟替卡松鼻喷雾剂80例为治疗组。治疗8周后,评估2组患者的症状、体征及总体改善情况,比较其疗效。结果:治疗组患者治疗有效率高于对照组(P<0.05),鼻塞、流涕及喷嚏症状均明显少于对照组(P<0.01),而2组患者鼻痒及咽痒症状差异无统计学意义(P>0.05)。治疗组患者鼻腔黏膜水肿及鼻腔分泌物均少于对照组(P<0.05和P<0.01);2组患者鼻腔黏膜苍白及结膜充血差异均无统计学意义(P>0.05)。结论:40℃3%氯化钠溶液鼻腔冲洗联合丙酸氟替卡松鼻喷雾剂治疗AR是一种安全、有效的治疗方法。
Objective： To investigate the effects of 40 ℃ 3% sodium chloride solution nasal irrigation combined with fluticasone nasal spray in the treatment of allergic rhinitis（ AR）. Methods： The clinical data of 160 patients with AR were retrospectively analyzed. The patients were randomly divided into the control group and treatment group（ 80 cases each group）. The control group and treatment group were treated with fluticasone propionate nasal spray and 40 ℃ 3% sodium chloride solution nasal irrigation,respectively. The symptoms,signs and general condition in two groups were evaluated after 8 weeks of treatment. Results： The effective rate in treatment group was higher than that in control group（ P〈0. 05）,the nasal obstruction,rhinorrhea and sneeze in treatment group were less than those in control group（ P〈0. 01）,and the symptom differences of rhinocnesmus and throat itching between two groups were not statistically significant（ P〈0. 05）. The nasal mucosal edema and nasal secretion in treatment group were less than those in control group（ P〈0. 05 and P〈0. 01）,but the differences of the nasal mucosa pale and conjunctival congestion between two groups were not statistically significant（ P〈0. 05）. Conclusions： The treatment of AR with 40 ℃ 3% sodium chloride solution nasal irrigation combined with fluticasone propionate nasal spray is safe and effective.
出处
《蚌埠医学院学报》
CAS
2016年第3期317-319,共3页
Journal of Bengbu Medical College
关键词
过敏性鼻炎
鼻腔冲洗
氯化钠溶液
丙酸氟替卡松
allergic rhinitis
nasal irrigation
sodium chloride solution
fluticasone propionate
