摘要
目的:了解原发性失眠(PI)的常见中医症状和证型的临床特征。方法:运用临床流行病学调查方法采集经治的1 379例PI患者的中医四诊资料,进行中医辨证分型,并对中医证型和典型症状进行分析。结果:1 379例PI患者中属于阳证1 101例(79.8%),属于阴证278例(20.2%);阳证患者中以肝郁化火证和阴虚火旺证多见,阴证患者以心脾两虚证多见。精神不振、神疲乏力、晨起思睡、健忘、注意力不集中是PI患者常见中医证型共有的症状和体征。PI患者的主要失眠症状依次为入睡困难、早醒、时睡时醒、多梦、通宵难眠和恶梦惊醒。入睡困难和早醒均可见于阴阳两证患者。而时睡时醒和通宵难眠多见于阳证患者(P<0.05,P<0.01),多梦多见于阴证患者(P<0.05,P<0.01),恶梦惊醒多见于阴证中的心虚胆怯证(P<0.05,P<0.01)。结论:PI患者阳证居多,阳证以肝郁化火证和阴虚火旺证多见,阴证以心脾两虚证多见,阴阳两证在主要失眠症状构成情况上有其自身特点。
Objective:To study the clinical features of traditional Chinese medicine(TCM) symptoms and syndromes of the patients with primary insomnia(PI).Methods:The symptoms signs,tongue and pulse parameters,the syndrome classification of 1 379 PI patients were investigated with methods of clinical epidemiologic survey.Classical symptoms and TCM syndromes were analyzed.Results:Among 1 379 PI patients,1 101 cases with yang syndrome and 278 cases with yin syndrome,accounting for 79.8% and 20.2% respectively.The syndromes of liver depression transforming into fire and hyperactivity of fire due to yin deficiency were dominant in patients with yang syndrome.Deficiency of both the heart and spleen syndrome was dominant in patients with yin syndrome.Lacking of energy,lassitude,morning drowsiness,forgetfulness and inattention were the common symptoms and signs in PI patients with yang syndrome and yin syndrome.There were 6 main insomnia symptoms in PI patients,including difficulty in falling asleep,early awakening,sometimes sleeping sometimes awake,dreaminess,failing in sleep all night and nightmares.Difficulty in falling asleep and early awaking were mostly seen in both patients with yang syndrome and yin syndrome.Sometimes sleeping sometimes awake and failing in sleep all night were mostly seen in patients with yang syndrome(P<0.05,P<0.01),while dreaminess was mostly seen in patients with yin syndrome(P<0.05,P<0.01).Nightmares was often seen in patients with syndrome of timidity due to deficiency of heart Qi(P<0.05,P<0.01).Conclusion:Among the patients with PI,yang syndrome was accounted for the majority.The syndromes of liver depression transforming into fire,hyperactivity of fire due to yin deficiency and deficiency of both the heart and spleen were dominant in PI patients with yang syndrome and yin syndrome respectively.Yang syndrome and yin syndrome had their own features in the insomnia symptoms.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2017年第4期1704-1707,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81173149)
福建省科技厅省属公益类科研院所基本科研专项(No.2015R1035-10)~~
关键词
原发性失眠
中医证型
症状
临床流行病学调查
Primary insomnia
TCM syndrome type
Symptom
Clinical epidemiologic survey
