摘要
目的:评价不同针刺深度对绝经过渡期患者生活质量和内分泌的影响。方法:将90例患者随机分配到深刺组(30例)、安慰针组(30例)和浅刺组(30例)。采用围绝经期生活质量量表(MENQOL)、以及生殖内分泌相关激素指标卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)的变化情况作为主要评价指标进行评价。结果:(1)3组患者MENQOL总分治疗后各时点比较,除第4周外,深刺组与安慰针组、浅刺组比较,差异均有统计学意义(P<0.05);而浅刺组与穴位安慰针组同期比较,仅在第8周时点比较,差异有统计学意义(P<0.05)。(2)MENQOL量表各维度比较:深刺组与安慰针组比较,血管舒缩症状维度评分在治疗后各时点以及心理、生理维度评分在治疗第8周、治疗后1个月和治疗后3个月,差异均有统计学意义(P<0.05);深刺组与浅刺组同期比较,生理维度评分在治疗第8周,差异有统计学意义(P<0.05)。(3)内分泌改变:深刺组与浅刺组均能降低LH水平,且深刺组下降幅度较浅刺组大,与安慰针组比较,差异有统计学意义(P<0.05)。结论:穴位不同针刺深度影响绝经过渡期患者生活质量,深刺疗效优于浅刺,浅刺优于安慰针刺;深刺以及浅刺对患者生殖内分泌有良性调整趋势,需待进一步研究。
Objective: To assess effects of different acupuncture depth on quality of life and hormone in menopausal transition. Methods: Ninty patients were randomly divided into three groups: deep acupuncture group(30), sham acupuncture group(30) and shallow acupuncture group(30). MENQOL and hormone(FSH, LH, E2) were used as evaluation index. Results:(1)Variance analysis of MENQOL scores showed significant differences between three groups(P<0.05) at every pionts, except that at four-week point.(2)For dimensions of MENQOL, there were significant differences in vasomotor dimension at every points, physical and psychiatric dimension at eight-week point, one month after treatment and three month after treatment point between deep acupuncture group and sham acupuncture group; there was significant differences only at eight-week point between deep acupuncture group and shallow acupuncture group.(3)For hormones, both deep acupuncture group and sham acupuncture group could reduce LH level, there were significant differences(P<0.05) between deep acupuncture group, sham acupuncture group. Conclusion: Analysis results of the trial indicated that depth of acupuncture can influence the efficacy. The curative effect of deep needling is better than that of shallow needling, and the shallow needling is better than that of sham needling. Deep needling and shallow needling have positive adjustment in reproductive endocrine. Further studies are needed.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2017年第10期4724-4729,共6页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
"十二五"国家科技支撑计划项目(No.2012B A I24B01)
国家自然科学基金项目(No.81173348)
广东省中医药局项目(No.20161210)~~
关键词
针刺深度
绝经过渡期
生活质量
生殖内分泌
临床研究
Depth of acupuncture
Menopausal transition
MENQOL
Reproductive endocrine
Clinical trial
