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3.0T MRI对颈动脉粥样硬化斑块成分的研究

Carotid Atherosclerotic Plaques:Studies with 3.0T MR
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摘要 目的:探讨3.0T MRI高分辨多序列成像评价颈动脉粥样硬化斑块成分的临床意义。方法:选择58例缺血性脑血管病患者,其中短暂性脑缺血发作(TIA)患者16例,脑梗死患者42例;运用3.0T MRI多序列(3D-TOF、DIR T1WI、FSE T2WI、PDWI)进行扫描,分析斑块成分。结果:58例患者中,17例(29.3%)有破损纤维帽,23例(39.7%)有完整厚纤维帽、18例(31.0%)有完整薄纤维帽;29例(50.0%)有斑块内出血,27例(46.6%)有斑块内钙化,42例(72.4%)有斑块内纤维化,49例(84.5%)有脂质池和坏死核心,脑梗死患者与TIA患者各类斑块成分所占比例比较,差异均无统计学意义(>005)。结论:3.0T MRI高分辨多序列成像有助于分析颈动脉粥样硬化斑块的成分,判断斑块的稳定性。 Objective: To investigate 3.0T MRI sequence signal characteristics of the intraplaque components of carotid atherosclerotic praque.Methods:Four 3.0T MRI sequences were used to analyze the carotid atherosclerotic plaques of 58 patients with carotid atherosclerotic plaque.The sequences used included 3D-TOF,DIR T1 WI,FSE T2 WI and PDWI.The patients were divided into transient ischemic attack(TIA) group containing 16 patients and cerebral infarction(CI)group containing 42 patients.Results:Of the 58 patients,17 had ruptured fibrous caps,23 had thick fibrous caps,18 had thin fibrous caps,29 had intra plaque haemorrhage,27 had calcification,42 had fibrous tissue in the plaque,49 had lipid rich necrotic cores.There was no statistic difference in plaque composition between the two groups.Conclusion:3.0 T MRI high resolution sequence image was helpful to analyzing the composition of carotid atherosclerotic plaques,judging the stability of the plaques.
出处 《农垦医学》 2015年第5期433-435,共3页 Journal of Nongken Medicine
基金 新疆生产建设兵团卫生科技计划项目
关键词 颈动脉 动脉硬化 磁共振成像 脑梗死 Carotid artery Atherosclerosis Magnetic resonance imaging Brain infarction
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参考文献8

  • 1Falk E.Stable versus unstable atherosclerosis:clinical aspects[J]. Am Heart J.2006,138(5Pt2):S421-S425.
  • 2Fischer JW,Steitz SA,Johnson PY,et al. Decorin promotes aortic smooth muscle cell calcification and eoloealizes to calcified regions in human atherosclerotic iesions[J].Artefioscler Thromb Vase Biol,2004,24(7):239-2396.
  • 3Bucay N,Sarosi I,DunstanCR,Morony S,et al.Osteoprotegerin deficient mice develop early onset osteoporosis and arterial calcification[J].Genes Dev,2008,12(4): 1260-1268.
  • 4Fisdher JW,Steitz SA,Johnson PY,et al.Decorin promotes aortic smooth muscle cell calcification and colocalizes to calcified regions in human atherosclerotic lesions[J].Arterioscler Thromb Vase Biol,2004,24(7):239-2396.
  • 5Demer L,L,Tintut Y.Mineral exploration: search for the mech- anism of vascular calcification and beyond :the 2009 Jeffrey M. Hoeg Award Lecture[J].Arterioscler Thromb Vase Biol,2009,23 (3): 1739-1743.
  • 6李树合,周定标,袁晓玲,孙同柱,余新光,许百男,卜博,蔡剑鸣.颈动脉粥样硬化不稳定斑块异质性的病理研究及高分辨MRI影像特点分析[J].中华神经外科杂志,2006,22(8):485-488. 被引量:28
  • 7Haley AP,Forman DE,Poppas A,et al.Carotid artery intima- media thickness and cognition in cardiovascular disease[J].Int J. Cardiol, 2007,121 (2): 148-154.
  • 8Underill HR,Kenvin WS,Hatsti,et al.mtmrmxl mmstretnem of ickmss in the common carotid artery by MRI:a cormson to intima media thickness by B.mode ultrasound.Magn Reson Imaging, 2010,24(7): 379-387.

二级参考文献9

  • 1Hennerici MG. The unstable plaque. Cerebrovasc Dis, 2004, 17( Suppl 3 ) : 17-22.
  • 2Lastas A, Graziene V, Barkauskas E, et al. Carotid artery atherosclerotic plaque: clinical and morphological immunohistochemi cal correlation. Med Sci Monit, 2004, 10: 606-614.
  • 3Toussaint JF, La Muraglia GM, Southern JF. et al. Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo. Circulation,1996, 94: 932-938.
  • 4Yuan C, Kerwin WS, Ferguson MS, et al. Contrast-enhanced high resolution MRI for atherosclerotic carotid artery tissue characterization. J Magn Reson Imaging, 2002, 15: 62-67.
  • 5Hatsukami TS, Ross R, Polissar NL, et al. Visualization of fibrous cap thickness and rupture in human atherosclerotic carotid plaque invivo with high-resolution magnetic resonance imaging. Circulation,2000, 102: 959-964.
  • 6Serfaty JM, Chaabane L, Tabib A, et al. Atherosclerotic plaques:classification and characterization with T2-weighted high-spatial-resolution MR imaging-an in vitro study. Radiology, 2001, 219:403- 410.
  • 7Yuan C, Mitsumori LM, Ferguson MS, et al. The in vivo accuracy of muhispectral MR imaging for identifying lipid-rich recrotic cores and intraplaque hemorrhage in advanced human carotid plaques.Circulation, 2001, 104 : 2051-2056.
  • 8李翎,段国升,周定标.颈动脉内膜切除术[J].中华神经外科杂志,1999,15(3):187-188. 被引量:3
  • 9徐永革,周定标.颈动脉疾病与缺血性卒中[J].中华神经外科杂志,2003,19(3):238-240. 被引量:16

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