摘要
目的探讨中晚期胰腺癌的中医病机。方法运用证素辨证方法，对临床84例确诊为中晚期胰腺癌患者进行中医证素研究，探讨其病位证素、病性证素的频数频率和总权值。结果84例患者中，病位证素总权值由高到低分别为脾、胃、肝、胆、肾、大肠、肺、心，其中脾与肝、胆、肾、大肠、肺、心病位证素比较，胃与胆、肾、大肠、肺、心病位证素比较，肝与肾、大肠、心病位证素比较，心与肾病位证素比较，心与肺病位证素比较，差异均有统计学意义（P值分别为0．004、0．030、0．025、0．040、0．037）；在病性证素中排前5位的是气虚、湿浊、热、血瘀、毒，与其他病性证素比较，差异有统计学意义（P〈0．01）。结论中晚期胰腺癌的病位主要在脾胃，病性属实者有气虚，属虚者有湿浊、热、血瘀、毒。
Objective To explore the TCM pathogenesis based on the analyses of TCM pattern elements. Methods TCM pattern elements of 84 patients with middle-late pancreatic cancer to analyze the TCM disease location and characteristics by their frequency and the contribution scores. Results A total of 84 patients were included, TCM disease location with the top 10 rank of the contribution scores were spleen, stomach, liver, gallbladder, kidney, intestine, lung, heart, spleen, stomach, while they were significantly higher than others （P〈0.05）. And the TCM pattern elements with the top 5 rank of the contribution scores were qi deficiency, dampness, heat, blood stasis, toxin, while they were significantly higher than others （P〈0.01）. Conclusions TCM disease locations of middle-late pancreatic cancer were mainly in spleen and stomach, and TCM pattern element were excessive patterns with qi deficiency, deficiency patterns with dampness, heat, blood stasis and toxin.
出处
《国际中医中药杂志》
2016年第5期400-402,共3页
International Journal of Traditional Chinese Medicine
基金
江苏省高校优势学科建设工程资助项目（YS2012ZYX105）
关键词
胰腺癌
证素
病机
治疗大法
Pancreatic cancer
TCM pattern elements
TCM pathogenesis
Treatment principle
