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NF-κB信号通路促进乳腺癌细胞增殖和转移机制的研究进展 被引量:4

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摘要 乳腺癌是在全球女性中发病率及致死率最高的恶性肿瘤之一,并且近几年的发病率呈上升趋势。研究证实炎症促进乳腺癌的发生,炎症因子IL-1β、IL-8和TNF-α是乳腺癌发生和发展的重要因素[1]。NF-κB信号通路通常能够被这些炎症因子诱导激活,并且参与炎症反应,促进肿瘤细胞的增殖、转移,与多种肿瘤的发生发展相关。大量研究证实激活的NF-κB信号通路,
出处 《天津医科大学学报》 2016年第3期270-272,共3页 Journal of Tianjin Medical University
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参考文献44

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二级参考文献40

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