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双联抗血小板治疗非心源性缺血性脑卒中临床疗效观察 被引量:13

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摘要 目的观察双联抗血小板在治疗非心源性缺血性脑卒中的临床疗效。方法选取医院2014年3月-2015年6月收治符合非心源性缺血性脑卒中诊断标准患者70例,随机分为观察组和对照组各35例。对照组给予阿司匹林药物治疗,观察组在对照组的基础上给予氯吡格雷治疗,分析比较2组治疗疗效。结果观察组治疗治愈率和总有效率为57.1%和85.7%明显高于对照组的37.2%和68.6%,差异有统计学意义(P<0.05);观察组的血浆黏度、血小板聚集率、全血低切黏度3项指标明显低于对照组,差异有统计学意义(P<0.05);在纤维蛋白原变化对比中,差异无统计学意义(P>0.05)。结论双联抗血小板在治疗非心源性缺血性脑卒中效果显著,可改善临床各项指标,缓解症状,在临床应用中值得推广。
作者 张合民
出处 《临床合理用药杂志》 2016年第14期33-34,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1中华医学会神经病学分会脑血管病学组指南协作组.中国缺血性脑卒中和TIA诊疗指南2010[J].中华神经科杂志,2010,43(2):154-160.
  • 2Peter M Rothwell, Sally C Howard, Eamon Dolan, et al.Prognostie signify canoe of visit-to-visit variability, maximum systolic blood pressure,and episodic hyper- tension[J].Lancet, 2010,375 (9718) : 895-905.
  • 3Meng X, Wang Y, Zhao X, et al. Validation of the Essen Stroke Risk Score and the Stroke Prognosis Instrument II in Chinese pa- tients. Stroke, 2011,42(12) :3619-3620.
  • 4Amerena JV, Walters TE, Mirzaee S, et al. Update on the man- agement of atrial fibrillation. Med J Aust, 2013, 199 (9): 592- 597.
  • 5Ozpolat C, Denizbasi A, Akoglu H, et al. Use of ABCD2 risk scoring system to determine the short-term stroke risk in patients presenting to emergency department with transient isehaemic at- tack. J Pak Med Assoc, 2013, 63(9) :1142-1146.
  • 6Emanuela F, Moushumi C, Jennifer M, et al. Continued Im- provement in Hypertension Management in England. Hyperten- sion, 2009,53(3) ..480-486.
  • 7ODonnell MJ, Xavier D, Liu L et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the IN- TERSTROKE study): a case-control study. Lancet, 2010, 376 (9735) : 112-123.
  • 8Peng B,Ni J, Anderson CS, et al. Implementation of a structured guideline- based program for the secondary prevention of ischemic stroke in China. Stroke,2014,F45(2) :515-519.
  • 9Prabhakaran S, Chong JY. Risk factor management for stroke prevention, 2014,20(2) :296-308.
  • 10Guo F, He D, Zhang W, et al. Trends in Prevalence, Aware- ness, Managementt and Control of Hypertension Among United States Adults, 1999 to 2010. J Am Coll Cardiol, 2012,60 (7) : 599-606.

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