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北京市昌平区成年人TG/HDL-C水平与糖尿病和糖尿病前期患病关系的研究 被引量:8

Relationship between triglyceride to high density lipoprotein cholesterol ratio and prevalence of diabetes and prediabetes in adults in Changping district,Beijing
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摘要 目的分析北京市昌平区成年人甘油三酯/高密度脂蛋白胆固醇(TG/HDL-C)水平与糖尿病和糖尿病前期患病的关系。方法研究对象为参加2013年北京市昌平区卫生与人群健康状况调查的18~79岁昌平区常住居民。研究对象个人信息通过问卷调查获得。根据TG/HDL-C在人群中分布情况,对男性及女性TG/HDL-C分别按照四分位数法分组。研究结局包括糖尿病、糖尿病前期以及糖尿病和糖尿病前期。结果调查对象3895人,其中男性1745人,女性2150人。调查结果显示,糖尿病患者、糖尿病前期人群、糖尿病和糖尿病前期患者分别为413、1016和1429人。经多因素logistic模型分析,在男性人群中,与〈0.66组相比,1.08~1.74组和≥1.75组糖尿病患病风险OR值(95%CI)分别为2.23(1.35~3.68)和2.36(1.43~3.91);糖尿病和糖尿病前期患病风险OR值(95%CI)分别为1.38(1.01~1.87)和1.80(1.32~2.45);≥1.75组糖尿病前期患病风险OR值(95%CI)为1.58(1.13~2.21)。在女性人群中,与〈0.57组相比,0.83~1.30组和≥1.31组糖尿病患病风险OR值(95%CI)分别为2.65(1.56~4.49)和3.72(2.23~6.22);糖尿病前期患病风险OR值(95%CI)分别为1.60(1.16~2.20)和2.20(1.59~3.04);糖尿病和糖尿病前期病患病风险OR值(95%CI)分别为1.78(1.32~2.39)和2.55(1.88~3.44)。结论随着TG/HDL-C水平的增加,糖尿病患病风险以及糖尿病前期患病风险均逐渐升高。 Objective To examine the association between triglyceride to high density lipoprotein cholesterol( TG / HDL-C)ratio and prevalence of diabetes and prediabetes in adults in Changping district,Beijing. Methods Data were collected from Changping Health and Population Health Status Survey in 2013 with a standard questionnaire. Participants aged 18- 79 years were divided into four groups according to quartiles of TG / HDL-C ratio in men and women,respectively. The outcome included diabetes,prediabetes and diabetes / prediabetes. Results A total of 3895 participants( 1745 men and 2150 women)were eligible for final data analysis. A total of 413 adults with diabetes,1016 adults with prediabetes,and 1429 adults with diabetes / prediabetes were recorded in the investigation. Multivariate logistic regression analysis indicated that the odds ratio( OR) of diabetes was 2. 23( 95% CI: 1. 35- 3. 68) and 2. 36( 95% CI: 1. 43- 3. 91),respectively,and the OR of diabetes/prediabetes was 1. 38( 95% CI: 1. 01- 1. 87) and 1. 80( 195% CI: 1. 32- 2. 45),respectively,in men with TG / HDL-C ratio of 0. 83- 1. 30 and ≥ 1. 31,and the OR of prediabetes was 1. 58( 95% CI: 1. 13- 2. 21) in men with TG / HDL-C ratio ≥1. 75 compared with men with TG / HDL-C ratio 〈0. 66. In women,the OR of diabetes in those with TG / HDL-C ratio of0. 83- 1. 30 and ≥ 1. 31 was 2. 65( 95% CI: 1. 56- 4. 49) and 3. 72( 95% CI: 2. 23- 6. 22) respectively,the OR of prediabetes was 1. 60( 95% CI: 1. 16- 2. 20) and 2. 20( 95% CI: 1. 59- 3. 04) respectively,and the OR of diabetes /prediabetes was 1. 78( 95% CI: 1. 32- 2. 39) and 2. 55( 95% CI: 1. 88- 3. 44) respectively compared with those with TG /HDL-C ratio 〈0. 57. Conclusion Increased TG / HDL-C ratio was significantly associated with increased risk of prevalence of both diabetes and prediabetes.
出处 《疾病监测》 CAS 2016年第4期329-333,共5页 Disease Surveillance
关键词 甘油三酯 高密度脂蛋白胆固醇 糖尿病 糖尿病前期 Triglyceride High density lipoprotein cholesterol Diabetes Prediabetes
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