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CT血管成像评估颈动脉粥样硬化与远期卒中的临床研究

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摘要 目的探讨CT血管成像评估颈动脉粥样硬化与远期卒中的临床价值。方法选取颈动脉粥样硬化患者120例作为观察组,同期选择除外颈动脉粥样硬化的120例患者作为对照组,2组都进行CT血管成像评估、临床资料的调查与远期随访。结果观察组的颈动脉狭窄程度多为重度与闭塞,而对照组多为中度与轻度;观察组的颈动脉斑块类型多为易损斑块,而对照组多为稳定斑块,对比差异有统计学意义(P〈0.05)。观察组与对照组随访6个月的卒中发生率分别为26.7%和5.0%,观察组明显高于对照组(P〈0.05);同时多因素Logistic回归分析,结果显示颈动脉狭窄程度(OR=3.327,95%CI:1.211~9.145)、颈动脉斑块形态(OR=3.699,95%CI:1.292~10.589)都为远期卒中的主要独立危险因素。结论 CT血管成像能有效评估颈动脉粥样硬化的狭窄程度与斑块形态,远期卒中的发生率也比较高,而狭窄程度与斑块形态与远期卒中密切相关,为此CT血管成像对判断预后具有重要的指导意义。 Objective To investigate the CT angiography assessment values for the carotid atherosclerosis and long-term stroke. Methods 120carotid atherosclerosis patients wete selected as the observation group, and selected excepted carotid atherosclerosis 120 patients as the control groupat the same periods, both groups were given the CT angiography assessment, surveyed clinical data and long-term followed-up. Results The degreeof stenosis of the observation group with more severe to occlusion, while the control group were more with mild to moderate; the carotid artery plaquetype in observation group were more vulnerable plaque, while the control group were more stable plaque, compared the difference in the two groupswere statistically significant (P〈0. 05). The followed six months of stroke rates in the observation group and the control group were 26. 7% and 5. 0%that the observation group were significantly higher than the control group (P〈0. 05); multivariate Logistic regression analysis showed that degreeof carotid stenosis (OR= 3. 327, 95% CI 1. 211-9. 145), carotid plaque morphology (OR=3. 699, 95% CI: 1. 292-10. 589) were the independent riskfactors for the long-term stroke. Conclusion CT angiography can effectively evaluate carotid atherosclerosis stenosis and plaque morphology, andthe incidence of long-term stroke is relatively high, while the degree of stenosis and plaque morphology are closely related to the forward stroke, forwhich CT angiography for prognosis has important guiding significances.
出处 《当代医学》 2016年第17期51-53,共3页 Contemporary Medicine
关键词 CT血管成像 颈动脉粥样硬化 卒中 狭窄程度 斑块形态 CT angiography Carotid atherosclerosis Stroke Stenosis Plaque morphology
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  • 1Wilbert S Aronow,Chandra K Nair,David Cosgrove.Assessment of neovascularization within carotid plaques in patients with ischemic stroke[J].World Journal of Cardiology,2010,2(4):89-97. 被引量:29
  • 2张旭静,邱伟波,黄久仪,王桂清.实验性动脉粥样硬化兔脑血管血液动力学研究[J].国际生物医学工程杂志,2006,29(4):197-199. 被引量:2
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33037
  • 4Agatston AS ,Janowitz WR,Hildner FJ ,et al. Quantification of coronary artery calcium using ultrafast computed tomography [J]. J Am Coil Cardiol,1990,15(4):827-832.
  • 5Rumberger JA, Simons DB, Fitzpatrick LA, et al. Coronary artery calcium area by electron-beam computed tomography and coronary atheroselerotic plaque area A histopathologie correlative study [ J ]. Circulation, 1995,92 ( 8 ) : 2157-2162.
  • 6Bluemke DA, Achenbach S, Budoff M, et al. Noninvasive coronary artery imaging: magnetic resonance angiography and multidetector computed tomography angiography: a scientific statement from the american heart association committee on cardiovascular imaging and intervention of the council on cardiovascular radiology and intervention, and the councils on clinical cardiology and cardiovascular disease in the young [ J ]. Circulation,2008,118 ( 5 ) :586- 606.
  • 7Brott TG,Halperin JL,Abbara S,et al. 2011 ASA/ACCF/AHA/ AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/ SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery DiseaseA Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscienee Nurses, American Association of Neurological Surgeons,American College of Radiology,American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery Developed in Collaboration With the American Academy of Neurology and Society of Cardiovascular Computed Tomography[ J]. J Am Coil Cardiol,2011,57(8) : 16-94.
  • 8Harloff A. Carotid plaque hemodynamics [ J ]. Intervent Neurol,2012,1 ( 1 ) :44-54.
  • 9Liu X, Xu G, Wu W, et al. Subtypes and one-year survival of first-ever stroke in Chinese patients:the Nanjing Stroke Registry [ J ]. Cerebrovase Dis ,2006,22 ( 2/3 ) : 130-136.
  • 10Barnett HJ,Taylor DW,Eliasziw M, et al. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis [ J ]. N Engl J ned, 1998, 339 (20): 1415-1425.

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