摘要
目的 探讨脂联素、脑钠肽、心衰超声指数与慢性心力衰竭的相关性。方法 选择2012年7月-2014年8月我院收治的90例慢性心力衰竭患者作为实验组,选择同期90例健康体检者作为对照组,检测两组APN和BNP水平,并计算心衰超声指数。结果 与对照组比较,实验组APN、BNP以及心衰超声指数均较高,差异有统计学意义（P〈0.05）;随着患者病情的加重,APN、BNP指标逐渐升高,差异有统计学意义（P〈0.05）;实验组APN水平与BNP呈正相关（r=0.503,P〈0.05）,APN水平与心衰超声指数呈正相关（r=0.237,P〈0.05）。结论 慢性心力衰竭患者的血清APN和BNP水平明显升高,患者心功能恶化越严重,升高越明显,在临床工作中需引起重视。
Objective To explore the correlation between adiponectin （APN）,brain natriuretic peptide （BNP）,HFEI and chronic heart failure （CHF）. Methods 90 patients with chronic heart failure who were admitted to our hospital from Ju- ly 2012 to August 2014 were selected in the experiment group,and 90 healthy subjects during the same period of time were selected in the control group.APN and BNP levels in the two groups of subjects were tested,and HFEI was calcu- lated. Results Compared with the control group,APN,BNP and HFEI were relatively higher in the experiment group,and the differences between the two groups were statistically significant （P〈0.05）;with patient＇s conditions becoming severe, APN and BNP gradually increased,and the differences were statistically significant （P〈0.05）;APN level in the experi- ment group was positive correlated with BNP （r=0.503,P〈0.05）,and APN level was positive correlated with HFEI （r= 0.237,P〈0.05）. Conclusion Serum APN and BNP levels are significantly increased in the patients with CHF.The more severe the patients＇ cardiac functions are,the higher the levels are increas6d,so attention should be paid to it in clinical works.
出处
《中国当代医药》
2016年第13期41-42,46,共3页
China Modern Medicine
