摘要
目的探讨抗结核药顿服法对老年肺结核患者胃肠道不良反应的影响，为老年肺结核患者服药管理提供新思路与方法。方法选取2013年2月至2014年4月收治的150例老年肺结核患者作为实验组，2014年5月至2015年8月收治的152例老年肺结核患者作为对照组，实验组采用睡前服药法，遵医嘱21：00-22：30睡前将每天的抗结核药量一次性服完，对照组采取早餐服药法，遵医嘱7：00～8：30空腹将每天的抗结核药量一次性服完。疗程均为2个月，2个月后比较两组服用抗结核药后出现的胃肠道反应及临床疗效。结果两组患者出现的胃肠道反应比较，差异有统计学意义（P〈0．05），两组患者临床疗效比较差异无统计学意义（P〉0．05）。结论老年患者采用睡前服用抗结核药能减少抗痨药物所致胃肠道不良反应。
Objective To investigate the antituberculotics adverse reactions in elderly patients with gastrointestinal tuberculosis, so as to provide new ideas and methods for the management of elderly patients with pulmonary tuberculosis medication. Methods Totally, 150 elderly patients with gastrointestinal tuberculosis from February 2013 to April 2014 were recruited as the experimental group and received the bedtime administration methods ,taken 1D anti tuberculosis drug 1 time service at 21 ： 130 to 22 ： 30 before sleep. While,152 elderly patients with gastrointestinal tuberculosis from May 2014 to August 2015 were recruited as the control group and received the method of medication for breakfast,taken 1D anti tuberculosis drug 1 time service at 7 ： 00 to 8 ： 30 with empty stomach. The course of treat- merit was 2 months, The gastrointestinal adverse reactions and clinical efficacy were compared after taking antitubereuloties for 2 mortths, Results There was signifi- cant difference in the gastrointestinal reactions between the two groups （ P 〈 0.05 ）. There was no significant difference in the clinical efficacy between the two groups （P 〉 0.05 ）. Conclusion Elderly patients with antituberculoties at bedtime can reduce the antitubereulotics drug - induced gastrointestinal side effects.
出处
《护理管理杂志》
2016年第4期276-277,共2页
Journal of Nursing Administration
基金
佛山市科技局(201108044)
关键词
结核药
老年患者
胃肠道不良反应
antituberculotics
elderly patients
gastrointestinal side effects
