摘要
目的通过检测肺癌患者血液中C-反应蛋白(CRP)、纤维蛋白原(FIB)以及血小板(PLT)水平,研究其在肺癌患者术后疗效中的临床意义。方法总结本院自2007年-2013年收治的196例肺癌患者的CRP、FIB和PLT水平,对病理类型、肿瘤转移及胸腔积液等进行回顾性分析。结果不同性别、年龄、吸烟史、病理类型肺癌患者PLT、FIB与CRP含量差异均无统计学意义(P>0.05)。PLT水平在脑转移组中升高,FIB水平在肝转移组中升高,CRP水平在肝转移组、肾上腺转移组、骨转移组中升高,差异均有统计学意义(P<0.05)。有胸腔积液组中PLT、FIB和CRP水平升高,差异均有统计学意义(P<0.05)。结论联合检测CRP、FIB和PLT能够作为肺癌患者预后有无转移及胸腔积液等的警示指标。
Objective To investigate the levels of C- reactive protein（ CRP）,fibrinogen（ FIB） and blood platelet（ PLT） in lung cancer and to explore its clinical significance in the prognosis. Methods The different pathological types,tumor metastasis and pleural effusion were retrospectively analyzed in 196 patients with expression levels of CRP,FIB and PLT from 2007 to2013. Results The differences on the PLT,FIB,CRP levels in different genders,ages,smoking history and pathologic types in patients with lung cancer was not statistically significant（ P 〈0. 05）. The levels of PLT in the brain metastasis group increased,FIB levels increased in the liver metastasis group,CRP levels increased in the liver metastasis group,adrenal metastasis group,bone metastasis group,and the differences were statistically significant（ P 〈0. 05）. The CRP,FIB and PLT levels increased in pleural effusion group,and the differences were statistically significant（ P 〈0. 05）. Conclusion The combined detection of CRP,FIB and PLT in lung cancer has certain value in judging the possibility of metastasis and pleural effusion.
出处
《中国卫生检验杂志》
CAS
2016年第9期1273-1275,共3页
Chinese Journal of Health Laboratory Technology
基金
浙江省医药卫生科研基金资助课题(2016KYB039)
