摘要
目的探究反流性食管炎患者采用莫沙必利和埃索美拉唑综合治疗的方法和疗效。方法选取2014年4月~2015年12月收治的77例反流性食管炎患者进行治疗,随机分组,实验组40例患者接受莫沙必利和埃索美拉唑的综合治疗,对照组37例患者选择常规埃索美拉唑的治疗,比较两组患者的治疗效果。结果实验组治疗有效率为95.0%,对照组治疗有效率为83.78%,实验组不良反应发生率为5.0%,对照组发生率为13.5%。对照组患者的不良反应率高于实验组,治疗效果低于实验组,差异有统计学意义（P〈0.05）。结论反流性食管炎患者采用莫沙必利和埃索美拉唑镁综合治疗,可进一步提高治疗效果,减少不良反应,安全性高。
Objective Comprehensive treatment method and its effect of mosapride combined with esomeprazole for reflux esophagitis are to be studied. Methods Chose 77 patients with reflux esophagitis who were treated in hospital from April 2014 to December 2015 and separated them into two groups at random. 40 patients in study group were given combination treatment of mosapride and esomeprazole,while another 37 patients in control group were given conventional Esomeprazole treatment,and then compared treatment effects between two groups. Results Patients’ treatment efficacy were 95.0% and 83.78% respective in study group and control group,while side-effect incidence were 5.0% and 13.5% respectively in study group and control group. Thus,side-effect incidence was higher but treatment efficacy was lower in control group compared to those in study group. There was a differential between two groups and such a differential had statistic value（P 〈 0.05）. Conclusion Mosapride combined with esomeprazole treatment is effective for reflux esophagitis,such a treatment is conducive to increasing treatment efficacy,reducing side-effect incidence with medication safety.
出处
《中国卫生标准管理》
2016年第7期84-85,共2页
China Health Standard Management
