摘要
目的探讨胃癌合并下肢深静脉血栓形成（deep venous thrombosis,DVT）的临床特点及治疗情况。方法回顾性分析2008年8月-2014年11月我院收治的22例胃癌合并下肢DVT患者的临床资料,分析其临床特点及治疗情况。结果 22例中,男性18例,女性4例,年龄36～84（62.2±15.0）岁。胃腺癌22例（100%）,Ⅳ期15例（68.2%）,中低分化18例（81.8%）。19例（86.4%）DVT发生于胃癌确诊后,其中1～3个月累计发生12例。腹部手术治疗10例,其中5例于术后1个月内发生血栓。经抗凝治疗12例（54.5%）,其中行下腔静脉滤器置入术3例,好转出院12例（54.5%）。结论胃癌确诊后及术后1～3个月是下肢DVT高发期,大部分确诊时为晚期且分化程度低,及时诊断、积极治疗可改善预后。
Objective To explore the clinical characteristics and treatment of gastric cancer with lower limb deep venous thrombosis（DVT）.Methods Clinical data about 22 gastric cancer patients with lower limb DVT from August 2008 to November 2014 in our hospital were retrospectively analyzed.The clinical characteristics and treatment were recorded.Results Of all 22 patients,there were 18 males and 4 females with average age of（62.2±15.0） years（ranging from 36 to 84 years）.Adenocacinoma was identified in 22（100%） patients,15（68.2%） patients were in stageⅣ and tumors in 18（81.8%） patients were moderately and/or low differentiated.DVT was diagnosed after the gastric cancer diagnosis in 19（86.4%） patients.After a definite diagnosis of cancer,12 patients experienced a thrombosis event within 3 months.Ten patients underwent abdominal surgery and 5 cases experienced a thrombosis event within the first month after surgery.Twelve（54.5%） patients received anticoagulant therapy and inferior vena cava filter placement was performed in 3 patients.Twelve（54.5%） patients improved when they were discharged.Conclusion The risk of DVT is the highest in the first 3 months after gastric cancer diagnosis or surgery.Most patients are diagnosed in late stage and have tumor with poor differentiation.Prompt diagnosis and aggressive treatment can improve the prognosis.
出处
《解放军医学院学报》
CAS
2016年第7期728-730,共3页
Academic Journal of Chinese PLA Medical School
关键词
胃癌
深静脉血栓形成
治疗
gastric cancer
deep venous thrombosis
therapy
