摘要
目的:探讨环孢素A联合科素亚在IgA肾病患者中的临床治疗效果。方法:选取2013年4月至2014年4月本院诊治的80例IgA肾病患者资料进行分析,采用随机数字方法将患者分为对照组和观察组,对照组采用科素亚治疗,观察组在对照组基础上联合环孢素A治疗,比较两组疗效。结果:观察组总有效率为95%,高于对照组的85%,观察组的满意率为95%,高于对照组的65%,差异具有统计学意义(P<0.05)。两组治疗后血浆白蛋白比较,差异无统计学意义(P>0.05);观察组治疗后24h尿蛋白定量显著低于对照组,血肌酐指标显著高于对照组,差异具有统计学意义(P<0.05)。结论:IgA肾病患者在科素亚治疗基础上联合环孢素A治疗效果理想,能够提高临床疗效。
Objective To investigate cyclosporine A combining with Cozaar clinical outcomes in patients with IgA nephropathy. Methods 80 cases of IgA nephropathy patients from April 2013 to April 2014 in our hospital were analyzed, and they were randomly divided into control method and the experimental group and the control group were losartan treatment, the experimental group combined with cyclosporine A treatment on the basis of the control group, two groups were compared. ResultsThe total effective rate for experimental group was 95 %, significantly higher than control group＇s 85 %; the experimental group satisfaction rate of 95 %, higher than 65 %（P 0.05）; after treatment serum albumin was not significantly different（P 0.05）; the experimental group after 24 hours of treatment of urinary protein excretion was significantly lower than the control group, blood creatinine index was significantly higher（P 0.05）. Conclusion IgA nephropathy patients ideal therapeutic effect combined with cyclosporine A treatment based on Cozaar, can improve clinical outcomes.
出处
《深圳中西医结合杂志》
2016年第7期75-76,共2页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
