摘要
目的探讨应用心脏康复模式对慢性心力衰竭患者心肺储备功能、生活质量及血清标志物N末端脑钠肽前体(NTproBNP)水平的影响。方法选取2013年4月至2015年4月该院心内科诊治的98例慢性心力衰竭患者为研究对象,按随机数字表法将患者分为对照组和心脏康复组,每组各49例。对照组患者予以常规慢性心力衰竭治疗与护理,康复组则在此基础之上分别予以强化心脏康复模式的干预方案,比较两组患者心肺储备功能、生活质量和NT-proBNP水平的变化。结果干预后,康复组患者心力衰竭相关知识的掌握率、去除高危因素重要性的知晓率较干预前显著提高(P<0.05),对照组与干预前比较差异无统计学意义(P>0.05);且康复组患者心力衰竭发生次数和间隔时间均显著优于对照组(P<0.05),但两组患者并发症的发生率比较,差异无统计学意义(P>0.05);干预后两组患者的生活质量评分均显著升高,且康复组患者生活质量各项指标得分值的增加幅度显著优于对照组(P<0.05);康复组心肺功能指标左心室收缩期末容量(LVESV)、左心室舒张期末容量(LVEDV)、左心室射血分数(LVEF)和最大通气量(MVV)均较干预前明显增加,且4项指标的改善水平均显著高于对照组(P<0.05);而其他指标干预前后差异无统计学意义(P>0.05);另外,干预后两组患者NT-proBNP水平均显著下降,且康复组的降低幅度较对照组更为明显(P<0.05)。结论心脏康复模式可明显提高慢性心力衰竭患者对疾病相关知识的掌握,降低复发率,延长间隔时间,提高生活质量,改善患者的心肺储备功能和NT-proBNP水平。
Objective To explore the effects of cardiac rehabilitation model on cardiac and pulmonary function,quality of life and NT-proBNP level in patients with chronic heart failure.Methods The 98 cases of chronic heart failure were selected from department of cardiology of Qijiang People′s Hospital from April 2013 to April 2015 and were randomly divided into control group and cardiac rehabilitation group,49 cases in each group.The patients of control group were treated with routine chronic heart failure treatment and nursing,while basised on the control group,the rehabilitation group were given the intervention program of the heart rehabilitation model.The changes of heart and lung function,quality of life and the level of NT-proBNP in the two groups were compared.Results In the rehabilitation group,after intervention,the awareness rate of the knowledge of heart failure,the awareness of the importance of risk factors was significantly improved than before intervention（P〈0.05）,but there was no significant difference in control group between bofore and after intervention（P〈0.05）.Moreover,the number of heart failure and the interval time of rehabilitation group were significantly better than the control group（P〈0.05）,while the incidence of complications in the two groups was not statistically significant（P〈0.05）.The quality of life of the two groups were significantly increased as comparison to before intervention,and the score of quality of life in the rehabilitation group was significantly higher than that in the control group（P〈0.05）.In the rehabilitation group,the heart and lung function indexes of LVESV,LVEDV and LVEF and MVV was significantly higher than those before intervention,and the improvement of four indicators of rehabilitation group were significantly higher than those of control group（P〈0.05）,but no significant difference were observed among other indicators before and after the intervention（P〈0.05）.In addition,the level of NT-proBNP in the two groups were significantly decreased,and the rehabilitation group was significantly lower than the control group（P〈0.05）.Conclusion Cardiac rehabilitation mode can significantly improve the knowledge of the disease in patients with chronic heart failure,reduce the recurrence rate,prolong the interval,improve the quality of life,the heart and lung function and NT-proBNP level.
出处
《检验医学与临床》
CAS
2016年第11期1462-1465,共4页
Laboratory Medicine and Clinic
基金
重庆市卫生局医学科研项目(2013-2-248)
