摘要
目的探讨不同剂型甲硝唑治疗滴虫阴道炎患者的临床治疗效果。方法选取2010年3月至2013年3月中山市坦背医院收治的滴虫阴道炎患者80例为研究对象,按治疗方案不同分为对照组和观察组,每组40例。对照组患者口服甲硝唑片治疗,观察组患者采用甲硝唑栓剂局部给药治疗,比较两组患者实验室检查结果及临床治疗效果。结果观察组患者滴虫数清除率为90.0%,显著高于对照组的67.5%,差异有统计学意义(P<0.05);观察组患者总有效率为92.5%,显著高于对照组的75.0%,差异有统计学意义(P<0.05);对照组患者不良反应发生率为15.0%,观察组未发生不良反应,差异有统计学意义(P<0.05)。结论甲硝唑治疗滴虫阴道炎具有一定的疗效,与口服甲硝唑片相比,甲硝唑栓剂局部给药治疗滴虫阴道炎患者的临床疗效更为显著。
Objective To compare and analyze the efficacy of different dosage forms of metronidazole in the treatment of trichomonal vaginitis.Methods randomly in our hospital from March 2010 to 2013 March were 80 cases of trichomonal vaginitis patients were divided into two groups;the control group oral metronidazole tablets for treatment,the observation group given metronidazole suppository for topical drug treatment;comparison of two groups of laboratory results and clinical therapeutic effect.Results observation trichomoniasis group number clearance rate was 90.0%,which was significantly higher than that of 67.5% in the control group,the two groups compared with statistical significance（P0.05）.The total effective rate in the observation group was 75.0%,which was significantly higher than that of the control group（P0.05）.The two groups were statistically significant（P92.5%）.The incidence of adverse reactions in the control group was 15.0%,the observation group was not adverse reactions,the two groups were statistically significant（P0.05）.Conclusion Oral metronidazole tablets compared,metronidazole suppository local drug treatment of trichomonas vaginitis clinical curative effect is more significant.
出处
《中国药物经济学》
2016年第5期34-36,共3页
China Journal of Pharmaceutical Economics
关键词
滴虫阴道炎
甲硝唑片
甲硝唑栓剂
治疗效果
Trichomonas vaginitis
Metronidazole tablets
Metronidazole suppository
Therapeutic effect
