肿瘤标志物检测在肝炎及肝硬化患者诊断和治疗中的应用价值被引量：3

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摘要目的探讨肿瘤标志物甲胎蛋白(AFP)、CA125、糖类抗原(CA199)和癌胚抗原(CEA)检测在肝炎及肝硬化诊断和治疗中的应用价值。方法选取2014年1月至2015年1月大连市第二人民医院收治的101例肝炎及肝硬化患者作为研究对象,按照病情严重程度将其分为慢性肝炎组(51例)和肝硬化组(50例)。另选取30例健康体检者作为对照组。检测3组受检者血清中AFP、CA125、CA199和CEA水平。结果肝硬化组和慢性肝炎组患者的血清AFP、CA125、CA199及CEA水平均明显高于对照组,且肝硬化组患者的血清AFP、CA125、CA199及CEA水平均明显高于慢性肝炎组,差异均有统计学意义(均P<0.05);肝硬化组和慢性肝炎组患者的AFP、CA125、CA199及CEA阳性检出率均明显高于对照组,且肝硬化组患者的AFP、CA125、CA199及CEA阳性检出率均明显高于慢性肝炎组,差异均有统计学意义(均P<0.05)。结论 AFP、CEA、CA199、CA125对诊断肝炎及肝硬化患者均具有重要意义,其均会随病情加重而增加。

作者潘善越曹德生王美媛

机构地区大连市第二人民医院

出处《中国药物经济学》 2016年第5期182-183,共2页 China Journal of Pharmaceutical Economics

关键词肝炎肝硬化肿瘤标志物甲胎蛋白 CA125 糖类抗原癌胚抗原

分类号 R575 [医药卫生—消化系统]

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