宫腔粘连病因学及治疗研究进展被引量：59

The Advances in the Etiology and Therapy of Intrauterine Adhesions

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摘要宫腔粘连是影响女性生殖健康的一个重要因素,随着医学的发展,其病因学的研究不断深入,流行病学调查、临床观察研究等方法揭示了宫腔粘连的高危因素为:妊娠后清宫术、剖宫产术后、滋养细胞疾病清宫术、苗勒管畸形、生殖道结核感染、诊断性刮宫、经腹子宫肌瘤剔除术、子宫动脉栓塞、宫腔镜手术、放置宫内节育器、产后出血子宫压迫性缝合等,这为其预防及治疗提供了思路。而医学工作者不断创新宫腔粘连治疗方法,从手术治疗、预防粘连再次发生、促子宫内膜再生治疗、术后再次评估治疗效果四方面进行科学研究,探寻治疗宫腔粘连的最优策略。利用干细胞移植技术治疗重度宫腔粘连并成功妊娠的病例报道,为宫腔粘连的治疗开辟了新思路。 Intrauterine adhesions is an important factor affecting the fertility of women. With the development of medicine, more and more risk factors were identified by epidemiological investigation and clinical observation research,including curettage after pregnancy, cesarean section, trophoblastic disease evacuation, M üllerian dut malformation, genital tuberculosis infection, diagnostic curettage, abdominal myomectomy, uterine artery embolization, hysteroscopic surgery, insertion of intrauterine device（IUD） and uterine compressive sutures for post-partum hemorrhage,etc. It can provide a useful method to prevent and cure intrauterine adhesions. The treatment strategy of intrauterine adhesions could be summarized in four main steps scientists. In order to find the best treatment strategy for intrauterine adhesions, scientists researched the following four respects：surgical treatment; re-adhesion prevention; restoring normal endometrium and post-operative assessment. The case report, using stem cells transplantation technique followed by conception in a patient of severe Asherman ′s syndrome,which opens up a new way for the treatment of intrauterine adhesions.

作者陈灿明王奕芳顾小燕(审校) 任卫娟

机构地区扬州大学医学院附属医院

出处《国际妇产科学杂志》 CAS 2016年第3期250-253,共4页 Journal of International Obstetrics and Gynecology

基金江苏省妇幼保健基金(F201337)

关键词流产人工刮宫术治疗宫腔粘连 Abortion induced Dilatation and curettage Therapy Intrauterine adhesions

分类号 R711.74 [医药卫生—妇产科学]

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