摘要
目的探讨Foxp3-924(rs2232365)基因位点多态性与产后抑郁的相关性。方法选取211例在越秀区光塔街社区卫生服务中心分娩的产妇进行回访研究,所有产妇均经PCR-SSP技术对Foxp3-924(rs2232365)基因位点分型。结果对比产后抑郁组与对照组产妇Foxp3-924各种基因型频率,结果显示均无差异(P>0.05)。结论产后抑郁和Foxp3-924(rs2232365)位点基因多态性无较大关联。
Objective To investigate the distribution of-924（ rs2232365） genotypes and to explore the correlation between gene loci polymorphism and postpartum depression. Methods In puerpera in Yuexiu district Guangta street community health center, there were 211 cases of childbirth study visits, who were confirmed by PCR-SSP technique Foxp3-924（ rs2232365） gene locus genotyping. Results Compared postpartum depression group and control group Foxp3-924 various genotypes,it showed no great difference（ P 〉 0. 05）. Conclusion It has no greater relevance between postpartum depression and Foxp3-924（ rs2232365） polymorphism loci.
出处
《广州医药》
2016年第3期1-4,共4页
Guangzhou Medical Journal
基金
广东省人口和计划生育委员会科研项目(20132054)
关键词
产后抑郁
基因位点
多态性
Postpartum depression
Gene locus
Polymorphism
