摘要
制备了活化玻碳电极,并采用循环伏安法研究了安乃近在该电极上的电化学行为。结果表明,该电极过程是一受吸附控制的不可逆过程。用线性扫描伏安法优化了实验参数,测定了浓度与峰电流Ipa的线性关系,在1.0×10^(-6)~5.0×10^(-5)mol·L^(-1)和5.0×10^(-5)~1.0×10^(-3)mol·L^(-1)范围内,有线性方程Ipa(μA)=0.43751+0.15494c(μmol·L^(-1));Ipa(μA)=7.03296+0.02556c(μmol·L^(-1)),检出限可达5.00×10^(-7)mol·L^(-1),回收率为94.0%~103.25%。该方法可用于药物中安乃近含量的测定。
The electro-chemical behavior of dipyrone was studied on the preparation of activated glassy carbon electrode by cyclic voltammetry.The result indicated that this electrode process was an irrrseveible one controlled by adsorption. Experimental parameters were optimized and the linear relationship between peak current and the concentration was measured by linear sweep voltammetry（ LSV）. A goodlinearity between the peak current and concentration of dipyrone in the range of 1. 0 × 10^-6～ 5. 0 × 10^-5mol·L^-1and 5. 0×10^-5～ 1. 0×10^-3mol·L^-1was found with a linear equation of Ipa（ μA） = 0. 43751＋0. 15494c（ μmol·L^-1） and Ipa（ μA） =7. 03296＋0. 02556c（ μmol·L^-1）,The detection limit was 5. 00×10^-7mol·L^-1.The recovery rate was 94. 0% ～ 103. 25%. This method can be used to measure the content of dipyrone in real samples.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2016年第6期833-836,共4页
Chemical Research and Application
关键词
安乃近
玻碳电极
循环伏安法
线性扫描伏安法
dipyrone
glassy carbon electrode
cyclic voltammetry
linear sweep voltammetry
