摘要
目的评价早期目标导向型镇静（EGDS）策略在ICU机械通气患者的应用效果。方法将2015年1~10月收治ICU符合纳入及排除标准的76例机械通气患者按随机数字法分为干预组和对照组,干预组42例采用EGDS策略;对照组34例采用标准化镇静策略。比较两组48h内浅镇静达标率、谵妄发生率及ICU住院日。结果干预组48h内浅镇静达标率显著高于对照组（P〈0.01）,谵妄发生率及ICU住院日显著低于/短于对照组（均P〈0.05）。结论 EGDS策略相对安全、可行,较标准化镇静策略能更有效使ICU机械通气患者达到早期浅镇静目标。
Objective To evaluate effect of early goal-directed sedation （EGDS） strategy in mechanically ventilated patients in ICU. Methods Seventy-six mechanically ventilated patients who were admitted in ICU from January to October 2015 and met inclusion as well as exclusion criteria were randomized into an intervention group and a control group, 42 of the patients in the intervention group received EGDS strate- gy, and the other 34 patients in the control group were given standard sedation strategy. The proportion of light sedation within the first 48 hours, the incidence of delirium and the length of ICU stay of the two groups were compared. Results The proportion of light sedation in the first 48 hours of the intervention group was significantly higher than the control group （P〈0. 01）, while the incidence of delirium and the length of ICU stay were significantly lower/shorter than the control group （P〈0.05 for both）. Conclusion The EGDS strategy is rela- tively safe and feasible, and it could achieve early light sedation more effectively than standard sedation.
出处
《护理学杂志》
CSCD
2016年第10期25-28,共4页
Journal of Nursing Science
关键词
重症监护病房
机械通气
镇静
早期目标导向型镇静
标准化镇静
谵妄
intensive care unit
mechanical ventilation
sedation
early goal-directed sedation
standard sedation
delirium
