摘要
目的观察宫血宁胶囊联合缩宫素对药物流产后出血的预防作用。方法选取2014年3月-2015年5月浙江省嘉兴市妇幼保健院收治的71例药物流产的孕妇进行研究分析。采用双盲、随机的方法将所有患者分为对照组37例和观察组34例。对照组患者药物流产后给予缩宫素,观察组患者药物流产后给予宫血宁胶囊联合缩宫素。药流后,对2组患者的药流疗效、完全流产孕妇药流后阴道出血量、完全流产孕妇药流后阴道出血持续时间和月经恢复时间进行对比分析。结果在药流之后,对2组孕妇药流疗效进行对比分析,结果显示,观察组患者的完全流产比例、不全流产比例、流产失败比例和对照组差异无统计学意义。对2组完全流产孕妇药流后阴道出血量进行比较,观察组的孕妇小于和等于月经量总数比例明显低于对照组（χ2=5.318,P〈0.05）。观察组药流后阴道出血持续时间明显小于对照组（P〈0.05）;对2组患者药流后月经恢复时间进行比较,差异无统计学意义。观察组完全流产孕妇月经经期天数优于对照组（P〈0.05）;月经周期天数相近,差异无统计学意义。结论宫血宁胶囊联合缩宫素对药物流产后出血有显著的预防作用,可有效降低药流后患者的出血量和出血时间,其是一种安全且有效的药流方法。
Objective To investigate the preventive action of Gongxuening capsule combined with oxytocin in treatment of bleeding after medical abortion. Methods 71 casess with medical abortion from March 2014 to May 2015,were randomly divided into observation group of 34 patients and control group of 37 patients. Conventional medical abortion forpregnant women as a control group,giving Gongxuening capsule drug for pregnant women in observation group. After medical abortion,the efficacy of the drug flow between two groups of patients,pregnant women,complete abortion drug flow vaginal bleeding,incomplete abortion pregnant drug flow duration and recovery time of menstruation comparative analysis. Results After medical abortion,medical abortion effect of the two groups of pregnant women were analyzed,the results showed that the proportion of complete abortion patients in the observation group,the proportion of incomplete abortion,abortion failure rates and the control group was not significant. Vaginal bleeding after two complete abortion drug flow comparing pregnant women in observation group and less than an amount equal to the total number of menstruation was significantly lower than control group（ χ2= 5. 318,P〈0. 05）. Observation group after the drug flow vaginal bleeding lasted significantly phrases in the control group（ P〈0. 05）; the recovery time of menstruation after medical abortion were compared two groups of patients. Observation group completely abortion menstrual period the number of days than the control group（ P〈0. 05）; similar to the menstrual cycle days,the difference was not statistically significant. Conclusion Gongxuening capsule combined with oxytocin on bleeding after medicinal abortion has a significant preventive effect,can effectively reduce the amount of bleeding and bleeding time in patients after the drug flow,which is a safe and effective medical abortion methods should be promoted and used in clinical.
出处
《中国生化药物杂志》
CAS
2016年第4期138-140,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
宫血宁胶囊
药物流产
阴道出血
Gongxuening capsule
medical abortion
vaginal bleeding
