摘要
目的探讨胃功能四项在胃部疾病和胃癌早期筛查中的应用效果。方法选取2014年1月至2015年10月门诊初诊为胃病的89例患者为实验组,40例健康体检者为对照组,分别检测血清胃功能四项[幽门螺杆菌(Hp)、胃蛋白原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ)、PGⅠ/PGⅡ比值)],结合临床资料进行统计分析。结果 PGⅠ、PGⅡ、PGⅠ/PGⅡ比值胃癌组<萎缩性胃炎组<胃溃疡组<浅表性胃炎组<对照组,组间比较差异有统计学意义(P<0.05);Hp阳性检出率胃癌组>萎缩性胃炎组>胃溃疡组>浅表性胃炎组>对照组,差异有统计学意义(P<0.05)。结论胃功能四项在胃部疾病和胃癌早期筛查中可作为重要的筛查指标,具有较高的应用价值。
Objective To investigate the application effects of gastric function four indexes on gastric disease and gastric cancer early screening. Methods From January 2014 to October 2015, 89 cases of newly diagnosed patients with stomach disease were enrolled as the experiment group, and 40 healthy subjects as the control group. The gastric function four indexes（Hp, PGI, PGⅡ, PGI/PGⅡ ratio） were detected and analyzed. Results PGI, PGH, PGI/PGⅡ ratio were getting hegher successively gastric cancer group, atrophic gastritis group, ulcer group, superficial gastritis group and control group, and there were significant differences （ P 〈 0. 05） ; Hp positive rate was getting lower successively in gastric cancer group, atrophic gastritis group, ulcer group, superfi- cial gastritis group and control group, and there were significant differences（P 〈 0. 05 ）. Conclusion The gastric function four in- dexes can be used as an important screening tool in the stomach disease and gastric cancer early screening with high value.
出处
《临床医学》
CAS
2016年第6期15-17,共3页
Clinical Medicine
关键词
胃功能四项
胃癌
胃部疾病
早期筛查
胃癌前疾病
Gastric function four indexes
Stomach cancer
Stomach diseases
Early screening
Precancerous disease
