摘要
靶向治疗是增加化疗药物疗效并减少其不良反应的重要途径之一,选择靶向药物载体系统非常重要.阿霉素在肝癌的靶向治疗中具有重要作用,阿霉素载体系统通过不同的作用机制靶向治疗肝癌,抑制和杀伤肿瘤细胞,降低了化疗药物的不良反应.文章对阿霉素靶向治疗肝癌的给药方式、药物载体和提高疗效的方式进行阐述,并对其他化疗药物及载体靶向治疗肝癌的作用进行了介绍,综述阿霉素在肝癌靶向治疗中的研究进展.
Targeted cancer therapy is one of the modalities to increase efficiency and decrease adverse effects of chemotherapy,and the selection of drug vector system is of importance for targeted therapy.An ideal adriamycin targeted vector system should have maximal efficacy and minimal adverse effects in inhibiting cancer cells through different mechanisms.This article reviews the recent progress in adriamycin targeted therapy,including the modes of adriamycin administration,the selection of drug vectors,as well as other chemotherapeutic drugs in targeted therapy of liver carcinoma.
出处
《中华全科医师杂志》
2016年第6期482-485,共4页
Chinese Journal of General Practitioners
关键词
肝肿瘤
阿霉素
靶向治疗
Liver neoplasms
Adriamycin
Cancer-targeted therapy