摘要
目的探究银锌霜和纳米银抗菌凝胶治疗Ⅱ度烧伤患者创面的临床效果。方法选取本院收治的102例Ⅱ度烧伤患者,随机分成3组:A组、B组以及对照C组,每组34例。所有患者均行常规清创处理,并给予补液、镇痛处理等。在此基础上A组加用银锌霜外敷治疗;B组采用纳米银抗菌凝胶外敷治疗;C组加用普通湿润烧伤膏外敷。及时记录并分析3组的平均愈合时间、抗生素使用时间、住院时间、住院费用、愈合率以及抗菌性等方面,SPSS 19.0软件分析组间的疗效差异性。结果 A、B两组的愈合时间、抗生素使用时间、住院时间均低于C组,差异显著,且A、B两组间差异也具有统计学意义。从愈合情况来看,A、B两组的愈合率明显优于C组,具有统计学意义。细菌阳性培养结果发现,A、B两组的阳性率(2.9%和5.9%)明显低于C组(17.6%),且A组的阳性率低于B组(2.9%vs.5.9%),差异显著。不良反应比较,A、B两组的不良反应例数显著低于C组,差异显著。结论银锌霜和纳米银抗菌凝胶均有良好的抗菌能力和促创面愈合效果,但存在差异,建议医护人员可以在早期使用银锌霜控制并预防创面感染,中后期使用纳米银抗菌凝胶,从而促进创面愈合。
Objective To explore the efficacy of silver-zinc cream and nano-silver antibacterial gel in the treatment of the patients with degreeⅡ burn.Methods A total of 102 patients with degreeⅡ burn were divided into3 groups.Group A（n=34）was treated with silver-zinc cream as external application.Group B（n=34）was treated with nano-silver antibacterial gel.Group C（n=34）was treated with ordinary moisture exposed burn ointment（MEBO）.All patients received routine debridement,fluid infusion and analgesic treatment.The mean healing time,duration of antibiotic use,length of stay（LOS）,hospitalization expenses,rate of healing and antibacterial property of all groups were recorded and compared.The differences of efficacy were analyzed with SPSS 19.0software.ResultsThe mean healing time,duration of antibiotic use and LOS of Group A and B were significantly lower than those of Group C,showing statistical significance.Moreover,there was difference between Group A and B.Group A and B had better rate of healing than Group C.From the positive bacteria cultivation,we discovered that the positive rate of Group A and B（2.9% and 5.9%）were lower than that of Group C（17.6%）,while the rate of Group A was lower than that of Group B（2.9% vs.5.9%）.Group A and B had fewer adverse reactions than Group C.Conclusion Both silver-zinc cream and nano-silver antibacterial gel have effective antibacterial ability and are able to accelerate wound healing,but some differences exist between them.We recommend medical care personnel to use silver-zinc cream as early treatment for regulating and preventing wound infection,and use nano-silver antibacterial gel in the middle and later periods to promote wound healing.
出处
《国外医学（医学地理分册）》
CAS
2016年第2期153-156,共4页
Foreign Medical Sciences：Section of Medgeography
关键词
银锌霜
纳米银抗菌凝胶
Ⅱ度烧伤
疗效
silver-zinc cream
nano-silver antibacterial gel
degreeⅡ burn
efficacy
