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16层螺旋CT在小细胞肺癌诊断中的临床价值 被引量:4

The clinical value of 16 - slice spiral CT in the diagnosis of small cell lung cancer
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摘要 目的观察小细胞肺癌(SCLC)的CT表现,探讨16层螺旋CT在SCLC诊断中的价值。方法选择55例SCLC和118例非小细胞肺癌(NSCLC)患者为研究对象,均经病理检查证实,所有患者在治疗前采用philips brilliance16螺旋cT进行平扫及增强扫描,比较两组肺癌CT表现(肿瘤分型、大小、密度形态;支气管闭塞、肺不张或阻塞性肺炎、纵隔肺门淋巴结肿大、淋巴结融合、纵隔血管受侵犯、胸腔积液的出现率)的差异。结果SCLC组与NSCLC组肿瘤分型及形态差异有统计学意义(Х^2=22.628、21.249,均P〈0.01),SCLC组以中央型为主,NSCLC组以不规则形和类圆形多见;中央型SCLC组和NSCLC组气管闭塞阳性、合并肺不张或阻塞性肺炎阳性率分别为57.78%和86.27%、62.22%和98.04%,中央型SCLC组低于NSCLC组(Х^2=9.830、20.131,均P〈0.01),中央型SCLC组和NSCLC组纵隔肺门淋巴结肿大阳性率、淋巴结融合阳性率、合并纵隔血管受侵犯阳性率分别为90.9%和49.15%,58%和15.52%,54.55%和7.63%,中央型SCLC组大于NSCLC组(Х^2=27.887、53.070、47.294,均P〈0.01)。结论16层螺旋cT可为鉴别诊断SCLC与NSCLC提供重要信息,圆形肿块、支气管通畅、肺门纵隔淋巴结肿大、肿大淋巴结融合不合并阻塞肺炎肺不张、合并纵隔血管侵犯等CT征象利于SCLC的诊断。 Objective To investigate the CT feature of small cell lung cancer( SCLC), and investigate the clinical value. Methods 55 patients with SCLC and 118 patients with non -small cell lung cancer(NSCLC) were selected as the study subjects. All the patients were confirmed by pathology,the CT feature of lung cancer were com- pared through unenhanced and enhanced scanning by philips brilliance 16 spiral CT. Results There were significant differences between the SCLC group and NSCLC group in tumor type and morphology( Х^2 = 22. 628,21. 249, all P 〈 0. 01 ). Central was the mainly type of SCLC, irregular shape and round was the mainly type of NSCLC. The positive rates of positive airway occlusion, pulmonary atelectasis or obstructive pneumonia in central SCLC group and NSCLC group were 57.78% and 86.27% ,62.22% and 98.04% ,which in central SCLC group were lower than NSCLC group ( Х^2 = 9. 830,20. 131, all P 〈 0.01 ). The Hilar and mediastinal lymph nodes positive rate ,fusion of lymph node - positive rate,combined positive rate of violations of mediastinal vessels in central SCLC group and NSCLC group were 90. 9% and 49.15% ,58% and 15.52% ,54.55% and 7.63% ,which in central SCLC group were greater than the NSCLC group(Х^2 =27.887,53.070,47.294,all P〈0.01). Conclusion 16 - slice spiral CT can provide important information for diagnosis of SCLC and NSCLC, the CT signs are conducive to the diagnosis of NSCLC, which contai- ning round mass, bronchial smooth, hilar and mediastinal lymph nodes, lymph nodes are not fused with obstructive pneumonia and atelectasis, mediastinal vascular invasion.
作者 涂毅
出处 《中国基层医药》 CAS 2016年第12期1776-1779,共4页 Chinese Journal of Primary Medicine and Pharmacy
关键词 肺肿瘤 体层摄影术 螺旋X线机 诊断 鉴别 Lung neoplasms Tomography, spiral X - ray machine Diagnosis Identification
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  • 1[34]Jacoulet P, Depierre A, Moro D, et al. Long-term survivors of small-cell lung cancer(SCLC): A French muticenter study. Grouper Oncologie de Langue Francaise[J]. Ann Oncol, 1997,8(10): 1009~1014
  • 2[35]Groen HJ, Fokkema E, Biesma B, et al. Paclitaxel and carboplatin in the treatment of small-cell lung cancer patients resistant to cyclophosphamide, doxorubicin, and etoposide: Anoncross-resistant cshedule[J]. J Clin Oncol, 1999, 17(3): 927~932
  • 3[36]Sonpavde G, Ansari R, Walker P, et al. Phase Ⅱ study of doxorubicin and paclitaxel as second-line chemotherapy of small-cell lung cancer: Hoosier Oncology Group Tral[J]. Am J Clin, 2000, 23(1): 68~70
  • 4[37]Nakanishi Y, Takayama K, Takano K, et al. Second-line chemotherapy with weekly cisplatin and irinotecan in patients with refractory lung cancer[J]. Am J Clin Oncol, 1999,22(4):399~402
  • 5[38]Tucker MA, Murray N, Shaw EG, et al. Second primary cancers related to smoking and treatment of small-cell lung cancer. Lung Cancer Working Cadre[J]. J Natl Cancer Inst, 1997,89(23): 1782~1788
  • 6[39]Johnson BE, Cortazar P, Chute JP. Second lung cancer in patients successfully treated for lung cancer [J]. Semin Oncol. 1997, 24(4): 492~499
  • 7[40]Karp DD. Lung cancer chemoprevention and mangement of carcinoma in situ[J]. Semin Oncol, 1997, 24(4): 402~410
  • 8[41]Perez EA, Loprinzi CL, Sloan JA, et al. Utility of screenig procedures for delecting recrence of disease after complete response in patients with small-cell lung carcinoma [J]. Cancer,1997, 80(4): 676~680
  • 9[1]Pass HI. eds. Lung cancer: principles and practice[J].Philadelphia: Lippincott-Raven, 1996:57~142
  • 10[2]Hamrick RM 3rd, Murgo AJ. Lactate dehydrogenase values and bone scans as predictors of bone marrow involvement in small-cell lung cancer [J]. Arch Intern Med, 1987, 147 (6):1070~1071

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