摘要
生物材料是用于人体组织和器官的诊断、修复或增进其功能的一类高技术材料,但由于蛋白质非特异性吸附现象的普遍存在,对这些材料造成污染,有时甚至危及生命安全。因此,研究具有抗蛋白质非特异性吸附性能的材料已成为生物医用材料领域的研究热点。本文首先介绍了蛋白质的吸附过程及材料抗蛋白质吸附的机理,重点综述了生物医学领域中广受关注的抗蛋白质吸附材料及其在生物医学领域中的应用,并对未来的发展趋势做了展望。
Biomaterials are used in human tissues and organs to diagnosis diseases, repair and inprove body functions as high-tech materials. Extensive attention and comprehensive research have been done in the field of tissue engineering, regenerative medicine and drug delivery. However, the general existence of nonspecific protein absorption usually leads to the pollutions of the biomaterials and sometimes even life-threatening consequences. Therefore, the research of non-specific protein resistant materials has become a hot topic in the field of biomedical materials. Firstly, this paper intrdouces the process of protein absorption and the mechanism of anti-protein materials resistant materials. Then it foucuses on the public concerning anti-protein materials and their applications in the biomedical field. Finally, it shows a developing trend of biomaterials.
出处
《高分子通报》
CAS
CSCD
北大核心
2016年第6期1-14,共14页
Polymer Bulletin
基金
国家自然科学基金(51573127
31271016
51073119)
关键词
抗蛋白质吸附材料
吸附机理
生物医学应用
综述
Protein resistant materials
Adsorption mechanisms
Biomedical applications
Review
