摘要
目的：评价心外膜脂肪组织厚度和冠状动脉疾病的相关性。方法：计算机检索PubMed、The Cochrane Library、EMbase、CBM、CNKI、VIP及WanFang Data,检索时限均为建库至2015年10月,收集关于心外膜脂肪组织厚度与冠状动脉疾病相关性的病例对照研究。由2位研究者按照纳入和排除标准独立筛选文献、提取资料和评价质量后,用STATA12.0软件进行Meta分析。结果：共纳入14个病例对照研究,3 162例研究对象,其中2 054例冠状动脉疾病患者,1 108例非冠状动脉疾病者。Meta分析显示：患冠状动脉疾病组的心外膜脂肪组织厚度大于无冠状动脉疾病者,它们之间的差异有统计学意义（SMD=0.67,95%CI：0.38-0.97,P=0.000）。结论：基于目前研究结果,可以确定心外膜脂肪组织厚度与冠状动脉疾病存在相关性,可能是一个评价冠心病风险的辅助指标。
Objective：To explore the relevance of the epicardial adipose tissue（EAT）thickness and coronary artery disease（CAD）.Method：The databases of PubMed,Cochrane Library,EMbase and CBM,CNKI,VIP and WanFang were retrieved with computers for collecting case-control study about the correlation between the EAT thickness and CAD from the time when they have built to October 2015.The data was extracted according to inclusion and exclusion criteria by two independent researchers.Then they evaluate the quality of them and give a Meta-analysis by using STATA 12.0software.Result：There were totally 14 case control studies included involving 3162 cases,2054patient with CAD and 1108 without.The results showed as follows：The difference of the level of EAT thickness between CAD group and the control group is significant（SMD=0.67,95%CI：0.38-0.97,P=0.000）.Conclusion：Based on the results of the present study we can determine the EAT thickness is associated with CAD.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2016年第6期562-565,共4页
Journal of Clinical Cardiology
