摘要
基于数据挖掘技术对中医治疗先兆流产文献分析时发现,白术、黄芩配伍使用频率较高。黄芩清热燥湿、泻火解毒、止血安胎,白术健脾益气、燥湿利尿、止汗安胎,两药配伍使用具有清热除湿,健脾安胎作用,临床治疗脾胃虚弱、湿热不化致先兆流产者。黄芩、白术乃"安胎圣药"起源于东汉张仲景《金匮要略·妇人妊娠病脉证并治篇》,被后世诸多医家用于治疗先兆流产,积累了丰富的研究文献和临床经验。目前对黄芩白术配伍治疗先兆流产的研究主要集中在其调节母胎界面免疫作用、支持妊娠黄体功能作用、抑制子宫平滑肌收缩作用三个方面。对其胚胎毒性研究方法主要为动物实验、体外模拟实验等,研究对象也只是单味黄芩、白术或其单体成分,其体内配伍应用的胚胎毒理需要进一步研究。
The literature analysis of treating threatened abortion with TCM Based on data mining techniques has discovered that the use frequency of compatibility of Huangqin（ Radix Scutellariae） and Baizhu（ Rhizoma Atractylodis Macrocephalae） is high.Huangqin can clear away heat and dry dampness,purge fire and remove toxicity,stop bleeding and protect fetus; Baizhu can activate the spleen and nourish qi,dry dampness and promote urination,stop sweating and protect fetus. The compatibility of them can clear away heat and remove dampness,activate the spleen and protect fetus. They are often used to treat threatened abortion due to weak spleen and stomach and stagnated heat and dampness. Huanglin and Baizhu are regarded as the best medicine for protecting fetus,which was recorded in Essentials from the Golden Cabinet by Zhang Zhong-jing of Eastern Han Dynasty and provides rich research literature and clinical experience of treating threatened abortion. At present the study of the compatibility of Huangqin and Baizhu focuses on regulating maternal-fetal interface immune function,supporting pregnant corpus luteum function role,and the inhibitory effect of uterine smooth muscle contraction. The embryo toxicity research methods mainly include animal experiments,simulation experiments in vitro,etc. The object of study is only a single Huangqin or Baizhu,or their monomer composition. The embryos toxicology of the compatibility of the application of in vivo needs further research.
出处
《河南中医》
2016年第6期1076-1078,共3页
Henan Traditional Chinese Medicine
基金
国家自然科学基金面上项目(编号:81273938)
关键词
先兆流产
黄芩
白术
配伍
threatened abortion
Huangqin（Radix Scutellariae）
Baizhu（Rhizoma Atractylodis Macrocephalae）
compatibility
