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术后肠麻痹发生机制和治疗的研究进展 被引量:26

Progress in the Research of Pathogenetic Mechanism and Treatment of Postoperative Ileus
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摘要 术后肠麻痹(POI)几乎发生于所有腹部手术之后,患者主要表现为恶心、呕吐、腹胀和排气、排便延迟,是术后肠道协调运动的暂时中断。本文介绍了POI的发生机制及治疗措施,指出POI患者在术后机体高分解代谢的情况下不能获得足量有效的营养,从而导致肠屏障受损,细菌内毒素移位,引起全身炎性反应综合征甚至多器官功能衰竭,最终导致患者术后感染并发症发生率增加、住院时间延长、住院费用增加、生活质量下降。但目前尚无避免POI的方法,所以术后如何改善患者已发生的POI,值得临床关注。 Postoperative ileus occurs after almost all abdominal operations, and patients mainly present nausea, vomiting, abdominal distension and delay of exhaust and defecation. It is a temporary interruption of postoperative bowel movement. The study introduced the pathogenetic mechanism and treatment measures of POI. POI patients can not acquire adequate and effective nutrition in the condition of high catabolism after surgery, which damages intestinal barrier, bacteria - endotoxin translocation, systemic inflammatory response syndrome and even muhiple organ failure. These factors lead to higher incidence of postoperative infectious complications, prolonged hospital stay, increase costs and decrease quality of life. But there is still no possible way to avoid the occurrence of postoperative ileus, so how to improve postoperative ileus is worth clinical concern.
出处 《中国全科医学》 CAS CSCD 北大核心 2016年第18期2223-2227,共5页 Chinese General Practice
关键词 消化系统外科手术 术后肠麻痹 治疗 Digestive system surgical procedures Postoperative ileus Therapy
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