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恙虫病17例临床特征分析 被引量:2

Clinical feature analysis of 17 cases with tsutsugamushi
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摘要 目的:分析恙虫病的临床特点,为临床诊断与治疗提供依据。方法:对2012年10-11月17例恙虫病住院患者进行回顾性分析。结果:17例患者均有接触草地、林地等野外活动史(其中16例职业为农民,1例为工人)。17例(100.00%)均有不同程度发热,9例(52.94%)皮肤溃疡或焦痂,12例(70.59%)皮疹,14例(82.35%)肝损害,8例(47.06%)肾损害,2例(11.76%)脾脏肿大,2例(11.76%)淋巴结肿大。误诊率47.06%。经阿奇霉素和/或左氧氟沙星治疗后17例均治愈。结论:恙虫病临床表现复杂多样,误诊率高,大环内酯类及喹诺酮类抗生素是治疗恙虫病的有效药物,皖北地区存在恙虫病疫源地。 Objective:To investigate the clinical features and diagnosis of tsutsugamushi to provide the basis of treatment. Methods: The clinical data of 17 patients with tsutsugamushi were from October to November 2012 retrospectively analyzed. Results:Seventeen patients(including 16 farmers and 1 worker) had a history of contact with grassland and woodland. The varying degrees fever in 17 cases( 100.00% ) ,skin ulcers or eschar in 9 cases(52.94% ) ,skin rash in 12 cases(70.59) ,liver injury in 14 cases(82.35% ) ,renal injury in 8 cases (47.06%), splenomegaly in 2 cases ( 11.76% ) and lymphadenovarix in 2 cases ( 11.76% ) were found. The misdiagnosis rate was 47.06%. All patients cured after the treatment with azithromycin and/or levofloxacin. Conclusions:The clinical manifestations of tsutsugamushi is complex and diverse, and its misdiagnosis rate is high. Macrolides and quinolones are the most effective drugs in the treatment tsutsugamushi. The epidemic focus is founded in northern Anhui province.
出处 《蚌埠医学院学报》 CAS 2016年第5期598-600,共3页 Journal of Bengbu Medical College
关键词 恙虫病 临床表现 tsutsugamushi clinical manifestation
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