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脑内糖皮质激素受体参与学习记忆机制研究进展 被引量:4

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摘要 正常下丘脑-垂体-肾上腺(hypothalamic-pituitaryadrenal,HPA)轴活动引起的体内糖皮质激素(glucocorticoids,GCs);人类以皮质醇为主,啮齿类动物以皮质酮为主,周期性波动是维持机体稳态、调节机体适应应激反应的必要条件,对记忆的获取及巩固起着重要的作用。GCs主要通过糖皮质激素受体(glucocorticoid receptors,GRs)的激活而发挥其生物学作用,GRs分为2种类型,即盐皮质激素受体(mineralocorticoid receptor,MR)和糖皮质激素受体,
出处 《中华全科医学》 2016年第8期1382-1385,共4页 Chinese Journal of General Practice
基金 国家自然科学基金(81472167) 蚌埠医学院研究生科研创新计划项目(Byycx1404)
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