摘要
目的探究妊娠期糖尿病(GDM)与妊娠期高血压疾病(HDCP)孕妇孕期体重变化情况及妊娠结局。方法选取2014年1月-2015年5月在该院进行妊娠期检查和分娩的孕产妇2 983例为研究对象,其中包括正常妊娠孕妇2 517例(A组)、GDM孕妇287例(B组)、HDCP孕妇126例(C组)和GDM合并HDCP孕妇53例(D组),对各组孕产妇孕10周、孕30周体重变化及妊娠结局进行比较。结果 4组孕妇年龄、孕10周、孕30周体重比较,差异有统计学意义(P均<0.05);4组孕10周、孕30周BMI及BMI变化值总体比较,差异均有统计学意义(P均<0.05),且B、C、D组上述指标均分别显著高于A组(P均<0.05),D组孕10周、孕30周BMI均分别显著高于B、C组(P均<0.05);4组孕妇胎膜早破、早产、剖宫产、产后出血、巨大儿及新生儿黄疸发生率比较,差异均有统计学意义(P均<0.05);B、C、D组上述不良妊娠结局发生率均显著高于A组(P均<0.05),且D组显著高于B、C组,差异有统计学意义(P均<0.05)。结论孕早期肥胖、孕期体重增加过多以及高龄人群是发生GDM和HDCP的高危人群。GDM和HDCP使得孕产妇与婴儿出现不良妊娠结局的风险加大,因此应该对高危人群进行合理干预,改善孕产妇健康状况。
Objective To explore maternal weight changes during pregnancy and pregnancy outcomes among women with gestational di- abetes mellitus （GDM） and hypertensive disorder complicating pregnancy （HDCP） . Methods A total of 2 983 pregnant women receiving pregnancy examination and giving birth to their babies in the hospital from January 2014 to May 2015 were selected and divided into group A （2 517 normal pregnant women）, group B （287 pregnant women with GDM）, group C （ 126 pregnant women with HDCP）, and group D （53 pregnant women with GDM and HDCP） . Maternal weight changes during pregnancy on the 10th and 30th gestational weeks and preg- nancy outcomes in the four groups were compared. Results There was no statistically significant difference in maternal age and weights on the 10th and 30th gestational weeks among the four groups （ P〈0. 05 ） . There were statistically significant differences in body mass index （BMI） on the 10th and 30th gestational weeks and change of BMI among the four groups （P〈0.05） . The above-mentioned indexes in group B, group C, and group D were statistically significantly higher than those in group A （P〈0. 05 ） . BMI values on the 10th and 30th gestational weeks in group D were statistically significantly higher than those in group B and group C （ P〈0. 05 ） . There were statistically significant differences in the incidence rates of premature rupture of fetal membrane, premature birth, cesarean section, postpartum hemor- rhage, macrosomia, and neonatal jaundice among the four groups （ P〈0. 05 ） . The incidence rates of premature rupture of fetal membrane, premature birth, cesarean section, postpartum hemorrhage, macrosomia, and neonatal jaundice in group B, group C, and group D were sta- tistically significantly higher than those in group A （P〈0. 05）, and the incidence rates of above-mentioned indexes in group D were statisti- cally significantly higher than those in group B and group C （P〈0.05） . Conclusion Obesity in early pregnancy, excessive body weight gain during pregnancy, and advanced age are high-risk population for GDM and HDCP. GDM and HDCP induce high risk of maternal and infantile adverse pregnancy outcomes, so the high-risk population should be intervened reasonably to improve maternal health.
出处
《中国妇幼保健》
CAS
2016年第13期2601-2603,共3页
Maternal and Child Health Care of China
关键词
妊娠期糖尿病
妊娠期高血压疾病
体重指数
Gestational diabetes mellitus
Hypertensive disorder complicating pregnancy
Body mass index
