摘要
目的观察分析重症感染病原菌的临床分布以及药敏规律,为临床准确使用抗菌药提供指导。方法回顾分析2014年1月—2015年12月在佳木斯市中心医院门诊及住院治疗的患者送检的血、尿、便等标本中分离到的400株病原菌,在以上各菌株中,来自呼吸内科、感染科和脑外科,占临床科室的47%,并对临床常用的14种抗菌药进行药敏试验。结果在400株病原菌中,金黄色葡萄球菌、铜绿假单胞菌和大肠埃希菌所占比例较大,分别占到32.5%、25%和19%。耐药实验结果表明,金黄色葡萄球菌对阿米卡星(83.4)、万古霉素(100)的敏感性较高,,铜绿假单胞菌对亚胺培南(91.4)、舒巴坦(83.3)、阿米卡星(82.3)的敏感度较高,大肠埃希菌则对阿米卡星(85.3),亚胺培南(100)的敏感度较高。结论实验菌株都有相对敏感的抗菌素,临床医师根据不同菌株的药敏程度合理使用抗菌素,并且医院各科室应规范消毒,避免交叉感染。
Objective To observe and analyze the clinical distribution and drug sensitivity of pathogenic bacteria in patients with severe infection.Convenient and accurate use of antimicrobial agents. Methods a retrospective analysis 2010-2015 years in Jiamusi central hospital outpatient and inpatient treatment of patients with submission of the blood to remove our hospital], urine and stool specimens isolated from 400 strains of pathogenic bacteria, and the clinical more common use of14 kinds of antimicrobial susceptibility test was performed. Results The results were representative of the data： in 400 strains of pathogenic bacteria, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli accounted for a large proportion, respectively, accounted for 32.5%, 25% and 19%. Resistance experiment results show that the Staphylococcus aureus has higher sensitivity to amikacin（83.4） and vancomycin（100）, Pseudomonas aeruginosa imipenem（91.4） and sulbactam（83.3）, amikacin（82.3） sensitivity high, Escherichia coli is to amikacin（85.3）, imipenem（100） sensitivity higher.Conclusion In each of the above strains, mostly from the Department of respiratory medicine, infection and brain surgery,and each strain have relatively sensitive to antibiotics, so in clinical medicine, physicians can according to the different strain sensitivity of drug rational use of antibiotics and hospital departments should standard disinfection, to avoid cross infection.
出处
《中外医疗》
2016年第16期37-39,共3页
China & Foreign Medical Treatment
关键词
重症感染
病原菌
药敏实验
Severe infection
Pathogenic bacteria
Drug sensitivity test
