摘要
目的:探讨分析奥曲肽对ERCP术后胰腺炎及胆管炎的预防效果.方法:选取甘肃省临潭县第一人民医院2015-02/2016-02进行ERCP手术的患者86例作为研究对象,根据入院顺序分为对照组(n=43)和观察组(n=43).两组患者术前用药一致,术中对照组予以生理盐水,观察组予以奥曲肽.观察两组患者ERCP手术前后血清淀粉酶含量及术后并发情况.结果:手术前,两组患者血清淀粉酶含量比较,差异无统计学意义(P>0.05),治疗3 h及24 h后,观察组血清淀粉酶含量均明显低于对照组,差异具有统计学意义(P<0.05);观察组和对照组并发症发生率分别为6.98%和23.26%,两组比较,差异具有统计学意义(P<0.05).结论:奥曲肽对ERCP术后胰腺炎及胆管炎预防效果良好,值得临床推广.
AIM:To analyze the precutionary effect of octreotide on pancreatitis and cholangitis after ERCP treatment. METHODS:A total of 86 patients under ERCP surgery admitted into The First People's Hospital of Lintan County, Gansu Province from February 2015 to February 2016 were selected as study objects. According to the order of admission, they were divided into the control group and the observation group, with 43 cases in each group. Two groups of patients before surgery received the same drug. During the surgery, patients in the control group were treated by saline, while patients in the observation group were treated by octreotide. The serum amylase levels and postoperative of two groups before and after operation were observed. RESULTS:Before the surgery, serum amylase enzyme level had no statistically significant difference between two groups( P〉0.05) . 3 h and 24 h after treatment, serum amylase enzyme level of the obserevation group was lower than that of the control group, with statistically significant difference(P〈0.05), and the complication rate of the observation group and the control group was 6. 98% and 23. 26%respectively, with statistically significant difference ( P〈0. 05 ) . CONCLUSION:Precautionary effect of octreotide on pancreatitis and cholangitis ofter ERCP treatment is good, and worthy of clinical promotion.
出处
《转化医学电子杂志》
2016年第7期54-55,共2页
E-Journal of Translational Medicine