摘要
目的探讨早发型重度子痫前期合并胎儿生长受限期待治疗的妊娠结局。方法选取2012年10月-2015年11月广东省惠州市第二妇幼保健院收治的早发型重度子痫前期患者80例,按照患者合并胎儿生长受限(FGR)的有无将其分为观察组和对照组,每组40例,观察组为合并FGR的患者,对照组为未合并FGR的患者。对所有患者均进行期待治疗,观察妊娠结局情况。结果观察组胎盘早剥发生率(15.0%)高于对照组(7.5%),分娩孕周(30.7±1.3)早于对照组(32.6±1.5),围生儿出生体重(1295.02±300.12)比对照组(1612.38±302.21)轻,围生儿死亡率(25.0%)显著高于对照组(12.5%),新生儿肺透明膜病发生率(3.3%)低于对照组(20.0%),心脏发育不全发生率(33.3%)高于对照组(14.3%),差异均有统计学意义(P<0.05)。结论给予早发型重度子痫前期合并胎儿生长受限患者进行期待治疗,不会增加孕产妇并发症,可借助延长患者的孕周,有效改善妊娠结局。
Objective To investigate pregnancy outcomes of expectant treatment among early onset severe preeclampsia merge with fetal growth restriction. Methods During Octomber 2012 to November 2015,80 patients with early onset severe preeclampsia were selected,40 cases combined with fetal growth restriction（ FGR） were divided into observation group,and the other 40 cases were divided into control group. All the patients were carried out expectant treatment,and to observe the outcome. Results Compare with control group,observation group had higher incidence of placental abruption（ 15. 0% vs 7. 5%）,earlier delivery weeks [（ 30. 7 ±1. 3） vs（ 32. 6 ± 1. 5） ],lighter perinatal child birth weight [（ 1295. 02 ± 300. 12） vs（ 1612. 38 ± 302. 21） ],higher perinatal child mortality（ 25. 0% vs 12. 5%）,lower incidence of hyaline membrane disease（ 3. 3% vs 20. 0%） and higher incidence of heart hypoplasia（ 33. 3% vs 14. 3%）,the difference was statistically significant respectively（ P〈0. 05）. Conclusion Expectant treatment on early onset severe preeclampsia patients with fetal growth restriction can＇t increase maternal complications,and can improve pregnancy outcome by prolonging gestation weeks.
出处
《中国妇幼卫生杂志》
2016年第3期60-62,66,共4页
Chinese Journal of Women and Children Health
关键词
早发型
重度子痫前期
胎儿生长受限
期待治疗
妊娠结局
early onset severe preeclampsia
fetal growth restriction
expectant treatment
pregnancy outcomes
