摘要
目的探究七氟醚与异氟醚吸入麻醉对直肠癌根治术后患者认知功能影响。方法选取我院行直肠癌根治术的56例患者,随机分组,各28例。研究组予以七氟醚吸入麻醉,对照组予以异氟醚吸入麻醉。比较两组患者术后MMSE评分。结果两组术后1 h MMSE评分均下降,研究组下降幅度低于对照组,差异有统计学意义(P<0.05);术后1 d,两组患者MMSE评分较术后1 h均上升,研究组高于对照组,差异有统计学意义(P<0.05)。结论七氟醚、异氟醚均会对行直肠癌根治术患者术后认知功能造成影响,但七氟醚影响较小。
Objective Explore the effects of sevoflurane and isoflurane inhalation anesthesia on cognitive function in patients after radical resection of for colorectal cancer. Methods 56 cases of radical resection of rectal cancer in our hospital were selected, random grouping, each of 28 cases. The research group received sevoflurane inhalation anesthesia, the control group received isoflurane inhalation anesthesia. MMSE scores were compared between the two groups. Results MMSE scores of two groups after 1 hours of surgery were significantly decreased, the decline in the study group was significantly lower than that in the control group, the difference was statistically significant（P〈0.05）, On the 1 d after operation, the MMSE scores of two groups were significantly higher than those of 1 hours after operation, the study group was significantly higher than that of the control group, the difference was statistically significant（P〈0.05）. Conclusion Sevoflurane and isoflurane can affect the cognitive function of patients caused by radical operation of rectal carcinoma,but the sevoflurane effect is small.
出处
《中国继续医学教育》
2016年第16期51-52,共2页
China Continuing Medical Education
关键词
七氟醚
异氟醚
直肠癌根治术
认知功能
Sevoflurane
Isoflurane
Radical resection for colorectal cancer
Cognitive function
