摘要
目的探讨中医疏风宣肺止咳汤剂治疗咳嗽变异性哮喘(CVA)患者的临床效果及对患者气道高反应性(BHR)的影响。方法将本科收治的120例CVA患者随机分为中医组、西医组,各60例。西医组给予沙美特罗氟替卡松吸入剂治疗,中医组在此基础上给予疏风宣肺止咳汤治疗,均以4 w为1个疗程,治疗1个疗程后进行效果评价。结果中医组治疗总有效率为91.67%,显著高于西医组78.33%(P<0.05);中医组的咳嗽减轻时间、夜咳停止时间、咳嗽消退时间均显著的短于西医组(P<0.05);治疗后,两组的嗜酸性粒细胞(EOS)、Ig E水平、气道传导率下降斜度(SGrs)值均较本组治疗前显著降低(P<0.05),最低反应阈值(Dmin)值较本组治疗前显著增高(P<0.05),且中医组治疗后上述指标改善情况更优于西医组(P<0.05)。结论中医疏风宣肺止咳汤剂结合西医治疗CVA能短时间内改善咳嗽症状,缓解BHR,效果显著。
Objective To explore the effects of Shufeng Xuanfei Zhike Decoction on the treatment of cough variant asthma （CVA） and bronchial hyperresponsiveness （BHR）. Methods A total of 120 CVA patients admitted to the department were randomly divided into traditional Chinese medicine （TCM） group and western medicine group （n=60, respectively）. The western medicine group was treated with fluticasone-salmeterol inhalation and the TCM group with Shufeng Xuanfei Zhike Decoction. The effects were evaluated after one course of treatment （four weeks）. Results The overall response rate of the TCM group was 91.67%, which was much higher than that of the western medicine group, 78.33%（P 〈 0.05）; the cough reduction time, night cough stop time and cough regression time of the TCM group were much shorter than those of the western medicine group （P 〈 0.05）; after treatment, the eosinophils （EOS）, IgE level and SGrs of the two groups were much lower than those of the corresponding group before the treatment （P 〈 0.05）; the minimum response threshold （Dmin） was much higher than that before the treatment （P 〈 0.05）; and the improvement of the above indexes of the TCM group was more obvious than that of the western medicine group （P 〈 0.05）. Conclusion TCM Shufeng Xuanfei Zhike Decoction combined with western medicine has remarkable effect on the treatment of CVA and can improve cough and relieve BHR in a short time
出处
《西南国防医药》
CAS
2016年第7期776-779,共4页
Medical Journal of National Defending Forces in Southwest China
