摘要
目的探讨12周及24周的有氧运动对急性心肌梗死患者心功能及氧代谢功能的影响。方法选取50例急性ST段抬高型心肌梗死并行急诊PCI的患者,随机分为有氧运动治疗(运动组)及非运动治疗(对照组)各25例,2组患者给予相同药物治疗,于入院后第8天、第12周及24周检查无氧阈值、峰值氧耗量、以及LVEF、N末端B型钠尿肽前体(NT-proBNP)水平。结果与对照组比较,运动组第12周及24周后无氧阈值[(15.05±5.80)ml/(kg·min)vs(14.78±1.50)ml/(kg·min),(15.94±0.86)ml/(kg·min)vs(14.43±1.82)ml/(kg·min),峰值耗氧量[(22.31±2.50)ml/(kg·min)vs(19.50±2.52)ml/(kg·min),(23.06±2.13)ml/(kg·min)vs(19.79±2.89)ml/(kg·min)],LVEF[(55.8±2.8)%vs(53.3±5.1)%,(56.5±2.9)%vs(53.7±5.2)%]明显升高,而NT-proBNP[(2171.4±1014.0)ng/L vs(2922.8±1342.6)ng/L,(1628.2±740.1)ng/L vs(2476.7±964.8)ng/L]明显降低(P<0.05,P<0.01)。与同组第8天比较,2组12、24周后无氧阈值、峰值氧耗量、LVEF明显升高,而NT-proBNP明显降低(P<0.05,P<0.01),运动组24周较12周时NT-proBNP明显降低(P<0.05)结论有氧运动治疗可以明显改善急性心肌梗死患者的心功能及氧代谢指标。
Objective To tudy the effect of 12-and 24-week aerobic exercise on the heart function and oxygen metabolism in ST segment elevation AMI patients.Methods Fifty ST segment elevation AMI patients after PCI were randomly divided into treatment group（n=25）and control group（n=25）and received the same drug therapy.Their anaerobic threshold（AT）,peak oxygen consumption,LVEF,NT-proBNP were measured after 8-day,12-and 24-week treatment.ResultsNo significant difference was found in AT,peak oxygen consumption,LVEF and NT-proBNP between the two groups after 8-day treatment（P〉0.05）.The AT,peak oxygen consumption and LVEF were significantly higher while the Nt-proBNP was significantly lower in treatment group than in control group after 12-and 24-week treatment[15.05±5.80ml/（kg·min）vs 14.78±1.50ml/（kg·min）,15.94±0.86 ml/（kg·min）vs 14.43±1.82 ml/（kg·min）;22.31±2.50 ml/（kg·min）vs 19.50±2.52ml/（kg·min）,23.06±2.13ml/（kg·min）vs 19.79±2.89ml/（kg·min）;55.8%±2.8%vs 53.3%±5.1%,56.5%±2.9%vs 53.7%±5.2%;2171.4±1014.0ng/L vs 2922.8±1342.6ng/L,1628.2±740.1ng/L vs 2476.7±964.8ng/L,P〈0.05,P〈0.01].The AT,peak oxygen consumption and LVEF were significantly higher while the NT-proBNP was significantly lower in two groups after 12-and 24-week treatment than after 8-day treatment（P〈0.05,P〈0.01）.The NT-proBNP was significantly lower in treatment group after 24-week treatment than after 12-week treatment（P〈0.05）.Conclusion Aerobic exercise can significantly improve the heart function,oxygen metabolism and prognosis in AMI patients.
出处
《中华老年心脑血管病杂志》
CAS
2016年第7期702-705,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
哈尔滨市科技局重大攻关课题(2013AA3BS043)
