摘要
目的归纳总结各类抗菌药物的免疫调节作用,以期为临床抗感染治疗提供更为全面合理有效的用药参考。方法本文在阅读大量国内外有关抗菌药物免疫调节作用的研究报道的基础上,对各类抗菌药物的免疫调节作用进行综述。结果综述了各类抗菌药物免疫调节作用机制及临床应用。结论各类抗菌药物除其具备的抗菌活性外,潜在的免疫调节作用对于抗感染治疗或抗炎治疗也存在很大的临床意义。
Objective The immunomodulatory effects of antimicrobial agents are reviewed here in order to provide comprehensive, reasonable and effective evidence for clinical appropriate application of antimicrobial agents. Methods The immunomodulatory effects of antimicrobial agents was summarized on the basis of a number of domestic and international reports. Results The possible mechanism of immunomodulatory effects and clinical application of different kinds antibacterial agents were described in this artical. Conclusion In addition to their antibacterial activity, potential immunomodulatory effects of antimicrobial agents might have significantly clinical value in anti-infection or anti-inflammatory treatment.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2016年第7期493-500,515,共9页
Chinese Journal of Antibiotics
基金
基金项目:基于p38/MAPK信号转导通路的多黏菌素E(colistin)免疫调节机制研究(81573472)
