摘要
以3,5-二羟基苯甲酸为起始原料,经羟基保护,还原,溴代,Arbuzor重排,Wittig-Horner反应,脱甲基保护及C-异戊烯基取代等反应,首次完成了天然产物Chiricanines C的全合成,总收率23%,其结构经-1H NMR,IR和EI-MS确证。
The total synthesis of natural product Chirieanines C with the overall yield of 23 % was first- ly achieved through protection of hydroxyl group, reduetion, bromination, Arbuzor rearrangment, Wit- rig -Homer reaction, demethylation and C-prenylation using 3,5-dihydroxybenzoyl acid as starting ma- terial. The strueture was confirmed by 1H NMR, IR and MS.
出处
《合成化学》
CAS
CSCD
2016年第7期616-619,共4页
Chinese Journal of Synthetic Chemistry
基金
宁夏自然科学基金资助项目(NZ15283)
宁夏"十三五"自治区化学工艺优势特色学科建设项目(宁教高办[2015]110号)
